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刺痛感蛋白抗体

供货周期：一周

品牌：

规格： 0.2ml/200μg

货号：

CAS号：

报价： ¥1

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产品介绍

在免疫化学技术中影响刺痛感蛋白抗体效率的因素主要有5个方面：①抗体对抗原的亲合性；②抗体对抗原的特异性；③抗原表位结构在该技术中是如何被改变的；④抗体与抗原结合的易接近性；⑤二级试剂的质量和类型

英文名称 Anti-Prickle

中文名称刺痛感蛋白抗体

别名 FLJ31627; FLJ31937; MGC138902; MGC138903; EPM1B; Prickle 1; Prickle homolog 1 (Drosophila); Prickle like protein 1; Prickle-like 1; Prickle1; REST-Interacting LIM Domain Protein; REST/NRSF interacting LIM domain protein 1; RILP; PRIC1_HUMAN.

刺痛感蛋白抗体浓度 1mg/1ml

规格 0.2ml/200μg

抗体来源 Rabbit

克隆类型 polyclonal

交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep

产品类型一抗

研究领域转录调节因子锌指蛋白表观遗传学

蛋白分子量 predicted molecular weight: 94kDa

性状 Lyophilized or Liquid

免疫原 KLH conjugated synthetic peptide derived from human Prickle

亚型 IgG

纯化方法 affinity purified by Protein A

储存液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复）

not yet tested in other applications.

optimal dilutions/concentrations should be determined by the end user.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

产品介绍 Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.

Function : Prickle is a LIM domain protein that appears to serve as a nuclear receptor for REST/NRSF, REST4, and possibly other transcription factors. The human protein is a 831 amino acid protein containing 3 N-terminal LIM domains and 3 C-terminal nuclear localization signals. It also contains 4 N-glycosylation sites, 2 PKA phosphorylation sites, and a C-terminal CIIS prenylation motif.

Subunit : Interacts with REST.

Subcellular Location : Nuclear Membrane

Tissue Specificity : Expressed at highest levels in placenta and at lower levels in lung, liver, kidney and pancreas. Expressed in thalamus, hippocampus, cerebral cortex, and cerebellum (in neurons rather than glia).

DISEASE : Defects in PRICKLE1 are the cause of progressive myoclonic epilepsy type 1B (EPM1B) [MIM:612437]. EPM1B is an autosomal recessive disorder characterized by myoclonus that progresses in severity over time, tonic-clonic seizures and ataxia.

Defects in PRICKLE1 may be a cause of susceptibility to neural tube defects (NTD) [MIM:182940]. Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy. Failure of neural tube closure can occur at any level of the embryonic axis. Common NTD forms include anencephaly, myelomeningocele and spina bifida, which result from the failure of fusion in the cranial and spinal region of the neural tube. NTDs have a multifactorial etiology encompassing both genetic and environmental components.

Similarity : Belongs to the prickle / espinas / testin family.

Contains 3 LIM zinc-binding domains.

Contains 1 PET domain.

Database links : UniProtKB/Swiss-Prot: Q96MT3.2

半个多世纪以来，抗体一直作为常用的研究工具，因此对其使用和储存已有丰富的经验。这些经验让人们知道如何对抗体进行操作，由于抗体的稳定性好，使用并不困难。抗体较其他蛋白不易变性，易于存放、纯化和标记。蛋白G和蛋白A等抗体结合蛋白的发现使得这项工作更具可行性。

选择合适的抗体对免疫化学技术的成功极为重要。没有任何一种来源的抗体能够满足本书所述的各种方法的要求。为了研究某一重要的抗原，应选用具有不同特性的多种抗体。在没有一套良好特性的抗体可用于研究机体中每一种蛋白之前，选择及制备适合各种技术要求的抗体非常必要。

J00552 人免疫球蛋白G Fc段受体Ⅰ(FcγRⅠ/CD64)ELISA试剂盒 Human ReceptorⅠfor the Fc region of immunoglobulin G,FcγRⅠ ELISA Kit 96T/48T

J00553 人粒细胞趋化蛋白-2(GCP-2/CXCL6)ELISA试剂盒 Human granulocyte chemotactic protein-2,GCP-2 ELISA Kit 96T/48T

J00554 人ω干扰素(IFN-ω/IFNB)ELISA试剂盒 Human Interferon ω,IFN-ω ELISA Kit 96T/48T

J00555 人糖基化依赖的细胞黏附分子(GlyCAM-1)ELISA试剂盒 Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA Kit 96T/48T

J00556 人干扰素调节因子(IRF)ELISA试剂盒 Human interferon Regulatory Factor,IRF ELISA Kit 96T/48T

J00557 人淋巴毒素β(LTB)ELISA试剂盒 Human lymphotoxinβ,LTB ELISA Kit 96T/48T

J00558 人淋巴毒素α(LTA)ELISA试剂盒 Human lymphotoxinα,LTA ELISA Kit 96T/48T

J00559 人CC趋化因子受体1(CCR1)ELISA试剂盒 Human CC-chemokine receptor 1,CCR1 ELISA Kit 96T/48T

J00560 人CX3C趋化因子受体1(CX3CR1)ELISA试剂盒 Human CX3C-chemokine receptor 1,CX3CR1 ELISA Kit 96T/48T

J00561 人肺部活化调节趋化因子(PARC/CCL18)ELISA试剂盒 Human pulmonary activation regulated chemokine,PARC ELISA Kit 96T/48T

J00562 人黏膜地址素细胞黏附分子(MAdCAM-1)ELISA试剂盒 Human mucosal addressin cell adhesion molecule-1,MAdCAM-1 ELISA Kit 96T/48T

J00563 人可溶性CD38(sCD38)ELISA试剂盒 Human Soluble Cluster of differentiation 38,sCD38 ELISA Kit 96T/48T

J00564 人可溶性CD21(CR2/sCD21)ELISA试剂盒 Human Soluble Cluster of differentiation 21,sCD21 ELISA Kit 96T/48T

J00565 人可溶性瘦素受体(sLR)ELISA试剂盒 Human Leptin Soluble Receptor,sLR ELISA Kit 96T/48T

J00566 人Toll样受体9(TLR-9/CD289)ELISA试剂盒 Human Toll-like receptor 9,TLR-9 ELISA Kit 96T/48T

J00567 人单核细胞趋化蛋白4(MCP-4/CCL13)ELISA试剂盒 Human monocyte chemotactic protein 4,MCP-4 ELISA Kit 96T/48T

J00568 人N钙黏蛋白/神经钙黏蛋白(N-Cad)ELISA试剂盒 Human Neural-Cadherin, N-Cad ELISA Kit 96T/48T

J00569 人肝素结合性表皮生长因子(HB-EGF)ELISA试剂盒 Human heparin-binding epidermal growth factor-like growth factor,HB-EGF ELISA Kit 96T/48T

J00570 人红细胞刺激因子(ESF)ELISA试剂盒 Human erythropoiesis stimulating factor,ESF ELISA Kit 96T/48T

J00571 人肿瘤坏死因子相关激活诱导因子(TRANCE)ELISA试剂盒 Human TNF related activation induced cytokine,TRANCE ELISA Kit 96T/48T

J00572 人上皮细胞粘附分子(Ep-CAM/CD362)ELISA试剂盒 Human Epithelial Cell Adhesion Molecule,Ep-CAM ELISA Kit 96T/48T

J00573 人巨噬细胞替代激活相关化学因子1(AmAC-1)ELISA试剂盒 Human Alternative macrophage activation-associated CC chemokine 1,AmAC-1 ELISA Kit 96T/48T

J00574 人可溶性血管内皮生长因子受体2(VEGFR-2/sFLK-1)ELISA试剂盒 Human soluble vascular endothelial growth factor receptor-2,VEGFR-2/sFLK-1 ELISA Kit 96T/48T

J00575 人胸腺基质淋巴细胞生成素(TSLP)ELISA试剂盒 Human thymic stromal lymphopoietin,TSLP ELISA Kit 96T/48T

J00576 人可溶性CD28(sCD28)ELISA试剂盒 human soluble cluster of differentiation 28,sCD28 ELISA Kit 96T/48T

J00577 人胸腺活化调节趋化因子(TARC/CCL17)ELISA试剂盒 Human thymus activation regulated chemokine,TARC ELISA Kit 96T/48T

J00578 人神经细胞粘附分子配体1(NCAM-L1/CD171)ELISA试剂盒 Human Neural cell adhesion molecule ligand 1,NCAM-L1 ELISA Kit 96T/48T

J00579 人可溶性凋亡相关因子配体(sFASL)ELISA试剂盒 Human soluble Factor-related Apoptosis ligand,sFASL/Apo-1 ELISA Kit 96T/48T

J00580 人细胞凋亡抑制因子(IAP)ELISA试剂盒 Human inhibitor of apoptosis,IAP ELISA Kit 96T/48T

J00581 人γ干扰素诱导单核细胞因子(MIGF/CXCL9)ELISA试剂盒 Human monocyte interferon gamma inducing factor,MIGF ELISA Kit 96T/48T

J00582 人干扰素诱导T细胞趋化因子(ITAC/CXCL11)ELISA试剂盒 Human Interferon inducible T-cell Chemoattractant,I-TAC ELISA Kit 96T/48T

J00583 人CD14分子(CDl4)ELISA试剂盒 Human cluster Of differentiation,CDl4 ELISA Kit 96T/48T

J00584 人白细胞共同抗原(LCA/CD45)ELISA试剂盒 Human leukocyte common antigen,LCA/CD45 ELISA Kit 96T/48T

J00585 人CD4分子(CD4)ELISA试剂盒 Human cluster Of differentiation,CD4 ELISA Kit 96T/48T

J00586 人CXC趋化因子配体16(CXCL16)ELISA试剂盒 Human CXC-chemokine ligand 16,CXCL16 ELISA Kit 96T/48T

J00587 人CXC趋化因子受体3(CXCR3)ELISA试剂盒 Human CXC-chemokine receptor 3,CXCR3 ELISA Kit 96T/48T

J00588 人γ干扰素诱导蛋白16/p16(IFI16/p16)ELISA试剂盒 Human interferon-inducible protein 16,IFI16/p16 ELISA Kit 96T/48T

J00589 人基质细胞衍生因子1a(SDF-1a/CXCL12)ELISA试剂盒 Human Stromal cell derived factor 1a,SDF-1a ELISA Kit 96T/48T

J00590 人可溶性CD86(B7-2/sCD86)ELISA试剂盒 Human soluble Cluster of differentiation 86,sCD86 ELISA Kit 96T/48T

J00591 人巨噬细胞移动抑制因子(MIF)ELISA试剂盒 Human Macrophage Migration Inhibitory Factor,MIF ELISA Kit 96T/48T

J00592 人组织因子途径抑制物(TFPI)ELISA试剂盒 Human Tissue factor pathway inhibitor,TFPI ELISA Kit 96T/48T

J00593 人干扰素诱导蛋白10(IP-10/CXCL10)ELISA试剂盒 Human interferon-inducible protein 10,IP-10 ELISA Kit 96T/48T

J00594 人巨噬细胞炎性蛋白5(MIP-5)ELISA试剂盒 Human macrophage inflammatory protein 5,MIP-5 ELISA Kit 96T/48T

J00595 人结缔组织生长因子(CTGF)ELISA试剂盒 Human connective tissue growth factor,CTGF ELISA Kit 96T/48T

J00596 人B细胞活化因子受体(BAFF-R)ELISA试剂盒 Human B cell activation factorr from the tumor necrosis factor family receptor,BAFF-R ELISA Kit 96T/48T

J00597 人血管内皮细胞生长因子受体3(VEGFR-3/Flt-4)ELISA试剂盒 Human Vascuoar endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA Kit 96T/48T

J00598 人血管内皮细胞生长因子受体1(VEGFR-1/Flt1)ELISA试剂盒 Human Vascuoar endothelial cell growth factor receptor 1,VEGFR-1/Flt1 ELISA Kit 96T/48T

J00599 人血管内皮细胞生长因子D(VEGF-D)ELISA试剂盒 Human Vascular Endothelial cell Growth Factor D,VEGF-D ELISA Kit 96T/48T

J00600 人血管内皮细胞生长因子C(VEGF-C)ELISA试剂盒 Human Vascular Endothelial cell Growth Factor C,VEGF-C ELISA Kit 96T/48T

J00601 人可溶性肿瘤坏死因子相关凋亡诱导配体(sTRAIL)ELISA试剂盒 Human soluble tumor necrosis factor-related apoptosis inducing ligand,sTRAIL ELISA Kit 96T/48T

J00602 人肿瘤坏死因子相关凋亡诱导配体4(TRAIL-R4)ELISA试剂盒 Human tumor necrosis factor-related apoptosis-inducing ligand 4,TRAIL-R4 ELISA Kit 96T/48T

J00603 人肿瘤坏死因子相关凋亡诱导配体3(TRAIL-R3)ELISA试剂盒 Human tumor necrosis factor-related apoptosis-inducing ligand 3,TRAIL-R3 ELISA Kit 96T/48T

J00604 人肿瘤坏死因子相关凋亡诱导配体1(TRAIL-R1)ELISA试剂盒 Human tumor necrosis factor-related apoptosis-inducing ligand 1,TRAIL-R1 ELISA Kit 96T/48T

J00605 人肿瘤坏死因子可溶性受体Ⅱ(TNFsR-Ⅱ)ELISA试剂盒 Human Tumor necrosis factor soluble receptor Ⅱ,TNFsR-Ⅱ ELISA Kit 96T/48T

J00606 人肿瘤坏死因子可溶性受体Ⅰ(TNFsR-Ⅰ)ELISA试剂盒 Human Tumor necrosis factor soluble receptor Ⅰ,TNFsR-ⅠELISA Kit 96T/48T

J00607 人基质细胞衍生因子1β(SDF-1β/CXCL12)ELISA试剂盒 Human Stromal cell derived factor 1β,SDF-1β ELISA Kit 96T/48T

J00608 人干细胞因子受体(SCFR)ELISA试剂盒 Human Stem Cell Factor Receptor,SCFR ELISA Kit 96T/48T

J00609 人正常T细胞表达和分泌因子(RANTES/CCL5)ELISA试剂盒 Human regulated on activation in normal T-cell expressed and secreted,RANTES ELISA Kit 96T/48T

J00610 人神经营养因子4(NT-4)ELISA试剂盒 Human Neurotrophin 4,NT-4 ELISA Kit 96T/48T

J00611 人神经营养因子3(NT-3)ELISA试剂盒人神经营养因子3(NT-3)ELISA Kit 96T/48T

J00612 人的神经生长因子(NGF)ELISA试剂盒 Human Nerve growth factor,NGF ELISA Kit 96T/48T

J00613 人巨噬细胞炎性蛋白3β(MIP-3β/ELC/CCL19)ELISA试剂盒 Human Macrophage Inflammatory Protein-3β,MIP-3β ELISA Kit 96T/48T

J00614 人巨噬细胞炎性蛋白3α(MIP-3α/CCL20)ELISA试剂盒 刺痛感蛋白抗体Human Macrophage Inflammatory Protein-3α,MIP-3α ELISA Kit 96T/48T

J00615 人巨噬细胞炎性蛋白1β(MIP-1β/CCL4)ELISA试剂盒 Human Macrophage Inflammatory Protein-1β,MIP-1β ELISA Kit 96T/48T

J00616 人巨噬细胞炎性蛋白1α(MIP-1α/CCL3)ELISA试剂盒 Human Macrophage Inflammatory Protein-1α,MIP-1α ELISA Kit 96T/48T

J00617 人单核细胞趋化蛋白3(MCP-3/CCL7)ELISA试剂盒 Human monocyte chemotactic protein 3,MCP-3 ELISA Kit 96T/48T

J00618 人单核细胞趋化蛋白2(MCP-2/CCL8)ELISA试剂盒 Human monocyte chemotactic protein 2,MCP-2 ELISA Kit 96T/48T

J00619 人单核细胞趋化蛋白1(MCP-1/CCL2/MCAF)ELISA试剂盒 Human monocyte chemotactic protein 1/monocyte chemotactic and activating factor,MCP-1/MCAF ELISA Kit 96T/48T

更多刺痛感蛋白抗体价格、批发价、品牌、厂家及抗体详细说明书，都可以免费咨询及索取。