效率的因素主要有5个方面：①抗体对抗原的亲合性；②抗体对抗原的特异性；③抗原表位结构在该技术中是如何被改变的；④抗体与抗原结合的易接近性；⑤二级试剂的质量和类型
英文名称 Anti-EDR1/PHC1
中文名称 早期发育调控蛋白1抗体
别 名 Early development regulatory protein 1; EDR1 PH1; hPH1; mPH1; PH1; Polyhomeotic-like protein 1; Rae28; PHC1_HUMAN.
早期发育调控蛋白1抗体浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 发育生物学 干细胞 转录调节因子 表观遗传学
蛋白分子量 predicted molecular weight: 105kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Human EDR1/PHC1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 PHC1 is a 1,004 amino acid nuclear protein that is a component of the PcG multiprotein PRC1 complex. Specifically, the PcG PRC1 complex modifies histones, remodels chromatin and mediates monoubiquination of Histone H2A. Other constituent proteins involved in the PcG PRC1 complex are Mel-18, Bmi-1, M33, MPc2, MPc3, RING1, Ring1b, as well as several others. Existing as a homodimer, PHC1 contains one FCS-type zinc finger and a SAM (sterile alpha motif) domain. PHC1 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Function : PHC1 is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The Polycomb group (PcG) genes are essential for maintenance of appropriate expression patterns of developmental master regulators, such as Hox genes, and thus are essential for proper development. PHC1 is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. PHC1, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein.
Subcellular Location : Nuclear.
Similarity : Contains 1 FCS-type zinc finger.
Contains 1 SAM (sterile alpha motif) domain.
Database links : UniProtKB/Swiss-Prot: P78364.3
半个多世纪以来，抗体一直作为常用的研究工具，因此对其使用和储存已有丰富的经验。这些经验让人们知道如何对抗体进行操作，由于抗体的稳定性好，使用并不困难。抗体较其他蛋白不易变性，易于存放、纯化和标记。蛋白G和蛋白A等抗体结合蛋白的发现使得这项工作更具可行性。
选择合适的抗体对免疫化学技术的成功极为重要。没有任何一种来源的抗体能够满足本书所述的各种方法的要求。为了研究某一重要的抗原，应选用具有不同特性的多种抗体。在没有一套良好特性的抗体可用于研究机体中每一种蛋白之前，选择及制备适合各种技术要求的抗体非常必要。
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J00180 人抗糖蛋白抗体(GP)ELISA试剂盒 Human anti-glycoprotein antibody，GP ELISA Kit 96T/48T
J00181 人抗单核细胞抗体(AMA)ELISA试剂盒 Human anti-Monocyte antibody，AMA ELISA Kit 96T/48T
J00182 人氧化低密度脂蛋白抗体(OLAb)ELISA试剂盒 Human oxidized lowdensity lipoprotein antibody，OLAb ELISA Kit 96T/48T
J00183 人沙眼衣原体(CT)ELISA试剂盒 Human Chlamydia trachomatis，CT ELISA Kit 96T/48T
J00184 人乙型肝炎表面抗原(HBsAg)ELISA试剂盒 Human hepatitis B virus surface antigen，HBsAg ELISA Kit 96T/48T
J00185 人抗乙型肝炎病毒核心抗体(HBcAb)ELISA试剂盒 Human anti-hepatitis B virus core antibody，HBcAb ELISA Kit 96T/48T
J00186 人抗乙型肝炎病毒核心IgM抗体(HBcAb-IgM)ELISA试剂盒 Human anti-hepatitis B virus core IgM，HBc-IgM antibody ELISA Kit 96T/48T
J00187 人抗乙型肝炎病毒表面抗体(HBsAb)ELISA试剂盒 Human anti-hepatitis B virus surface antibody，HBsAb ELISA Kit 96T/48T
J00188 人抗乙型肝炎病毒e抗体(HBeAb)ELISA试剂盒 Human anti-hepatitis B virus e antibody，HBeAb ELISA Kit 96T/48T
J00189 人抗流行性出血热病毒抗体IgM (EHF)ELISA试剂盒 Human anti-epidemic hemorrhagic fever virus IgM antibody，EHF IgM ELISA Kit 96T/48T
J00190 人抗狂犬病毒抗体(anti-RV)ELISA试剂盒 Human anti-rabies virus antibody， anti-RV ELISA Kit 96T/48T
J00191 人抗甲型肝炎病毒IgM抗体(anti-HAV)ELISA试剂盒 Human anti-hepatitis A virus IgM antibody，anti-HAV ELISA Kit 96T/48T
J00192 人抗甲型肝炎病毒IgG抗体(anti-HAV)ELISA试剂盒 Human anti-hepatitis A virus IgG antibody，anti-HAV ELISA Kit 96T/48T
J00193 人抗副流感病毒IgM抗体(anti-PIV IgM)ELISA试剂盒 Human anti-parainfluenza virus IgM antibody， anti-PIV IgM ELISA Kit 96T/48T
J00194 人抗丁型肝炎病毒抗体(anti-HDV)ELISA试剂盒 Human anti-hepatitis D virus antibody，anti-HDV ELISA Kit 96T/48T
J00195 人抗丙型肝炎病毒抗体(anti-HCV)ELISA试剂盒 96T/48T
J00196 人抗斑疹伤寒抗体(anti-typhus-Ab)ELISA试剂盒 Human anti-typhus antibody ELISA Kit 96T/48T
J00197 人抗流行性出血热病毒抗体IgG (EHF)ELISA试剂盒 Human anti-epidemic hemorrhagic fever virus IgG antibody，EHF IgG ELISA Kit 96T/48T
J00198 人包虫抗体IgG ELISA试剂盒 Human echinococcus antibody IgG ELISA Kit 96T/48T
J00199 人百日咳毒素(PT)ELISA试剂盒 Human Pertussiu Toxin，PT ELISA Kit 96T/48T
J00200 人白色念珠菌(C.albicans)ELISA试剂盒 Human Candida Albicans，C.albicans ELISA Kit 96T/48T
J00201 人流行性乙型脑炎抗体IgG(JE IgG)ELISA试剂盒 Human Coronaviruses IgG ELISA Kit 96T/48T
J00202 人沙眼衣原体抗体(CT)ELISA试剂盒 Human Chlamydia trachomatis，CT ELISA Kit 96T/48T
J00203 人血吸虫(schistosoma)ELISA试剂盒 human schistosoma ELISA Kit 96T/48T
J00204 人轮状病毒抗原(RV Ag)ELISA试剂盒 Human Rotavirus antigen，RV Ag ELISA Kit 96T/48T
J00205 人军团菌抗原(LP Ag)ELISA试剂盒 Human Legionella pneumophila antigen，LP Ag ELISA Kit 96T/48T
J00206 人大肠菌素(colicin)ELISA试剂盒 human colicin ELISA Kit 96T/48T
J00207 人腺病毒抗原(ADV-Ag)ELISA试剂盒 Human Adenovirus Antigen，ADV-Ag ELISA Kit 96T/48T
J00208 人旋毛虫抗体(Trichinella Ab)ELISA试剂盒 Human Trichinella antibody ELISA Kit 96T/48T
J00209 人破伤风抗体(Tetanus Ab)ELISA试剂盒 Human Tetanus Antibody ELISA Kit 96T/48T
J00210 人钩端螺旋体IgM(Lebtospira)ELISA试剂盒 Human Lebtospira IgM ELISA Kit 96T/48T
J00211 人钩端螺旋体IgG(Lep IgG)ELISA试剂盒 Human Leptospira IgG，Lep IgG ELISA Kit 96T/48T
J00212 人布鲁氏菌抗体IgG(Brucella Ab IgG)ELISA试剂盒 Human Brucella Antibody IgG，Brucella Ab IgG ELISA Kit 96T/48T
J00213 人水痘带状疱疹病毒IgM(VZV-IgM)ELISA试剂盒 Human Varicella zoster virus IgM，VZV IgM ELISA Kit 96T/48T
J00214 人水痘带状疱疹病毒IgG(VZV-IgG)ELISA试剂盒 Human Varicella zoster virus IgG，VZV-IgG ELISA Kit 96T/48T
J00215 人军团菌抗体IgA(LP Ab-IgA)ELISA试剂盒 Human Legionella antibody IgA，LP Ab-IgA ELISA Kit 96T/48T
J00216 人军团菌抗体IgM(LP Ab-IgM )ELISA试剂盒 Human Legionella antibody IgM，LP Ab-IgM ELISA Kit 96T/48T
J00217 人军团菌抗体IgG(LP Ab-IgG)ELISA试剂盒 Human Legionella antibody IgG，LP Ab-IgG ELISA Kit 96T/48T
J00218 人腮腺炎病毒IgM ELISA试剂盒 Human paramyxovirus parotitis IgM ELISA Kit 96T/48T
J00219 人腮腺炎病毒IgG ELISA试剂盒 Human paramyxovirus parotitis IgG ELISA Kit 96T/48T
J00220 人EB病毒IgM(EBv IgM)ELISA试剂盒 Human epstein-barr virus IgM，EBv IgM ELISA Kit 96T/48T
J00221 人EB病毒IgA(EBv IgA)ELISA试剂盒 Human epstein-barr virus IgA，EBv IgA ELISA Kit 96T/48T
J00222 人EB病毒IgG(EBv IgG)ELISA试剂盒 Human epstein-barr virus IgG，EBv IgG ELISA Kit 96T/48T
J00223 人登革热抗体(DF-Ab)ELISA试剂盒 Human dengue fever antibody，DF ELISA Kit 96T/48T
J00224 人流感病毒抗体IgG(FLU)ELISA试剂盒 Human Influenza viruses IgG，FLU ELISA Kit 96T/48T
J00225 人腺病毒IgM(ADV-IgM)ELISA试剂盒 Human Adenovirus IgM，ADV-IgM ELISA Kit 96T/48T
J00226 人腺病毒IgG(ADV-IgG)ELISA试剂盒 Human Adenovirus IgG，ADV-IgG ELISA Kit 96T/48T
J00227 人轮状病毒(RV)IgM ELISA试剂盒 Human Rotavirus，RV IgM ELISA Kit 96T/48T
J00228 人艾柯病毒IgM(ECHO IgM)ELISA试剂盒 human EchoVirus IgM，ECHO IgM ELISA Kit 96T/48T
J00229 人抗呼吸道合胞病毒抗体(RSV)ELISA试剂盒 Human anti-respiratory syncytial virus antibody，RSV ELISA Kit 96T/48T
J00230 人麻疹病毒IgM(MV IgM)ELISA试剂盒 Human measlesvirus IgM，MV IgM ELISA Kit 96T/48T
J00231 人柯萨奇病毒IgM(Cox V-IgM)ELISA试剂盒 Human Coxsackie virus IgM，Cox V-IgM ELISA Kit 96T/48T
J00232 人柯萨奇病毒IgG(Cox V-IgG)ELISA试剂盒 Human Coxsackie virus IgG，Cox V-IgG ELISA Kit 96T/48T
J00233 人结核菌杆抗体IgG(TB-Ab IgG)ELISA试剂盒 Human tuberculosis antibody IgG，TB-Ab IgG ELISA Kit 96T/48T
J00234 人庚型肝炎病毒IgM(HGV-IgM)ELISA试剂盒 Human Hepatitis G virus IgG，HGV-IgG ELISA Kit 96T/48T
J00235 人戊型肝炎病毒IgM(HEV-IgM)ELISA试剂盒 Human Hepatitis D virus IgM，HDV IgM ELISA Kit 96T/48T
J00236 人戊型肝炎病毒IgG(HEV-IgG)ELISA试剂盒 human hepatitis E virus IgG，HEV-IgG ELISA Kit 96T/48T
J00237 人丁型肝炎IgM(HDV IgM)ELISA试剂盒 早期发育调控蛋白1抗体Human Hepatitis D virus IgM，HDV IgM ELISA Kit 96T/48T
J00238 人丁型肝炎IgG(HDV IgG)ELISA试剂盒 human Hepatitis D virus IgG，HDV IgG ELISA Kit 96T/48T
J00239 人丙型肝炎IgM(HCV-IgM)ELISA试剂盒 Human Hepatitis C virus IgM，HCV-IgM ELISA Kit 96T/48T
J00240 人丙型肝炎IgG(HCV-IgG)ELISA试剂盒 Human Hepatitis C virus IgG，HCV-IgG ELISA Kit 96T/48T
J00241 人糖蛋白130(gp130)ELISA试剂盒 Human glucoprotein 130，gp130 ELISA Kit 96T/48T
更多早期发育调控蛋白1抗体价格、批发价、品牌、厂家及抗体详细说明书，都可以免费咨询及索取。
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