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当前位置： 顺元生物 > 蛋白质/多肽 > Recombinant Human RO-52/SS-A

Recombinant Human RO-52/SS-A

供货周期： 一周
品牌：
规格： 5μg
货号： PRO-328
CAS号：
报价： ¥700
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产品介绍
Synonyms 52 kDa Ro protein, Sjoegren syndrome type A antigen, SS-A, Ro(SS-A), 52 kDa ribonucleoprotein autoantigen Ro/SS-A, Tripartite motif-containing protein 21, RING finger protein 81, TRIM21, RNF81, RO52, SSA1, SSA, RO-52.
Introduction TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The 52 kDa Ro protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. Ro/SSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Ribonucleoprotein particle is composed of a single polypeptide and one of four small RNA molecules. The RoSSA is present in all mammalian cells studied but has no known function. At least 2 isoforms are present in nucleated and red blood cells, and tissue specific differences in Ro/SSA proteins were identified.
Description TRIM21 Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated  molecular mass of 54,922 Dalton.
TRIM21 is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Source Sf9 insect cells.
Physical Appearance Sterile Filtered clear solution.
Formulation TRIM21 is supplied in 20mM HEPES pH-7.5, 0.01mM EDTA and 0.02% SDS.
Storage Conditions Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
Avoid multiple freeze-thaw cycles.
Purity Greater than 90% as determined by SDS-PAGE.
Coating concentration 0.3-0.65 µg/ml (depending on the type of ELISA plate and coating buffer). Suitable for labeling of functional groups.
Applications Western blot with:
a) SLE sera (secondary Sjogren’s syndrome).
b) Monoclonal anti-hexa-His-tag antibody.
Immunological functions 1. Binds IgG-type human auto-antibodies.
2. Standard ELISA test (checker-board analysis of positive/negative sera panels including CDC international reference sera).
Usage Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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工商信息

企业名称

上海顺元生物科技有限公司

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信用代码

310116002748169

成立日期

2012-11-29

注册资本

50

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上海顺元生物科技有限公司

公司地址

上海市七莘路2465号

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Recombinant Human RO-52/SS-A由上海顺元生物科技有限公司为您提供，货号PRO-328，规格：5μg，CAS号：，如您想了解更多关于Recombinant Human RO-52/SS-A价格、Recombinant Human RO-52/SS-A结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human RO-52/SS-A外，还可为您提供猴糜蛋白酶样弹性蛋白酶1(ELA1)ELISA kit、人转化生长因子β1(TGFB1)抗体ELISA kit、人转化生长因子β2(TGFB2)抗体ELISA kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，顺元生物客户服务电话，售前、售后均可联系。
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