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当前位置: 顺元生物 > 蛋白质/多肽 > Recombinant Human Mothers Against Decapentaplegic Homolog 3

Recombinant Human Mothers Against Decapentaplegic Homolog 3

供货周期: 7天
品牌:
型号: 5μg
货号: PRO-751
报价: ¥700
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产品介绍
Synonyms MADH3, JV15-2, HSPC193, HsT17436, MGC60396, DKFZp586N0721, DKFZp686J10186, SMAD3, Mothers against decapentaplegic homolog 3, Mothers against DPP homolog 3, MAD homolog 3, Mad3, hMAD-3, SMAD family member 3, SMAD 3, hSMAD3.
Introduction SMAD3 is part of the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD3 has a role as a transcriptional modulator activated by TGF-Beta and is involved in the regulation of carcinogenesis. SMAD3 mutations are related with the pathogenesis of human osteoarthritis. SMAD3 expression take part in tumor suppression in the premature stages of gastric carcinogenesis. SMAD3 is involved in nuclear translocation of beta-catenin.
Description SMAD3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 445 amino acids (1-425) and having a molecular mass of 50.2 kDa. SMAD3 is fused to a 20 amino acid His-Tag at N-Terminus and purified by standard chromatography techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless solution.
Formulation The SMAD3 protein solution contains 20mM Tris-HCl pH-8, 0.1M NaCl, 0.1mM DTT and 20% glycerol.
Stability Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Amino Acid Sequence MGSSHHHHHH SSGLVPRGSH MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRS LDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN PMSPAHNNLD LQPVTYCEPA FWCSISYYEL NQRVGETFHA SQPSMTVDGF TDPSNSERFC LGLLSNVNRN AAVELTRRHI GRGVRLYYIG GEVFAECLSD SAIFVQSPNC NQRYGWHPAT VCKIPPGCNL KIFNNQEFAA LLAQSVNQGF EAVYQLTRMC TIRMSFVKGW GAEYRRQTVT STPCWIELHL NGPLQWLDKV LTQMGSPSIR CSSVS.
Purity Greater than 90.0% as determined by SDS-PAGE.
Usage ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
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上海顺元生物科技有限公司

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信用代码

310116002748169

成立日期

2012-11-29

注册资本

50

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Recombinant Human Mothers Against Decapentaplegic Homolog 3由上海顺元生物科技有限公司为您提供,货号PRO-751,规格:5μg,CAS号:,如您想了解更多关于Recombinant Human Mothers Against Decapentaplegic Homolog 3价格、Recombinant Human Mothers Against Decapentaplegic Homolog 3结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Human Mothers Against Decapentaplegic Homolog 3外,还可为您提供人谷氨酸脱羧酶(GAD1)自身抗体ELISA kit、牛骨成型蛋白受体1A(BMPR1A)ELISA kit、豚鼠胰淀粉酶α2A(AMY2A)ELISA Kit等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,顺元生物客户服务电话,售前、售后均可联系。
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