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Recombinant Human Retinoic Acid Receptor Responder 2

供货周期：一周

品牌：

规格： 5μg

货号： PRO-788

CAS号：

报价： ¥700

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产品介绍

Synonyms	Chemerin, TIG2, Tazarotene-induced gene 2 protein, Retinoic acid receptor responder protein 2, RAR-responsive protein TIG2, RARRES2, HP10433.
Introduction	RARRES2 is a secreted chemotactic protein that initiates chemotaxis through the ChemR23 G protein-coupled seven-transmembrane domain ligand. RARRES2 is upregulated by the synthetic retinoid tazarotene and found in a vast variety of tissues. RARRES2 acts as an adipokine, and is truncated on both termini from the proprotein. RARRES2 is structurally related to the cathelicidin precursors, cystatin C and kininogens. RARRES2 promotes calcium mobilization and chemotaxis of immature dendritic cells and macrophages. RARRES2 is secreted as a precursor of little biological activity, which requires proteolytic cleavage of its COOH-terminal domain to be exchangeed into a potent and highly specific agonist of ChemR23. RARRES2 signals via its receptor, ChemR23 (CMKLR1), as a positive regulator of adipocyte differentiation and metabolic function. The Chemerin receptor acts as a coreceptor for SIV and some primary HIV-1 strains. The Chemerin receptor has another ligand, called tazarotene-induced gene
Description	RARRES2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 138 amino acids and having a total molecular mass of 16 kDa. RARRES2 Human Recombinant is purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	The RARRES2 protein was lyophilized from 0.02% TFA.
Solubility	It is recommended to reconstitute the lyophilized Chemerin in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Stability	Lyophilized Chemerin although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Chemerin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity	Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino Acid Sequence	MELTEAQRRG LQVALEEFHK HPPVQWAFQE TSVESAAVDTP FPAGIFVRLE FKLQQTSRK RDWKKPECKV RPNGRKRKCL ACIKLGSEDK VLGRLVHCPI ETQVLREAEE HQETQCLRVQ RAGEDPHSFY FPGQFAFS.
Usage	Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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企业名称

上海顺元生物科技有限公司

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信用代码

310116002748169

成立日期

2012-11-29

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上海顺元生物科技有限公司

公司地址

上海市七莘路2465号

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Recombinant Human Retinoic Acid Receptor Responder 2由上海顺元生物科技有限公司为您提供，货号PRO-788，规格：5μg，CAS号：，如您想了解更多关于Recombinant Human Retinoic Acid Receptor Responder 2价格、Recombinant Human Retinoic Acid Receptor Responder 2结构式、批发、用途等信息，欢迎咨询。除供应Recombinant Human Retinoic Acid Receptor Responder 2外，还可为您提供植物1,5-二磷酸核酮糖羧化酶／加氧酶（RuBisCO）ELISA Kit、牛脂多糖/内毒素(LPS) ELISA kit、豚鼠胰淀粉酶α2A(AMY2A)ELISA Kit等试剂，公司有专业的客户服务团队，是您值得信赖的合作伙伴，顺元生物客户服务电话，售前、售后均可联系。

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Recombinant Human Retinoic Acid Receptor Responder 2

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