A series of volatile organic compounds (VOCs) in drinking water are determined using In-Tube Extraction comprehensive GC/time-of-flight mass spectrometry (ITEX GCxGC/TOF-MS). A method for determining these compounds has been established and detection limits for a selected number of VOCs are depicted. Detection limits were below 20 ng/L for all compounds. A comparison with ‘classical’ Purge & Trap GC/MS is made. Repeatablility experiments revealed an RSD of less than 20% for all the compounds, well within the demands of the Flemish decree on drinking water