液质血液样品自动化进样平台

瑞士Prolab公司发布了基于CTC PAL开发的干血点(Dry Blood Spot)自动化平台SCAP，集血卡打孔、进样、过滤、浓缩、切换到LC-MS系统为一体，极大的提高了血卡的分析通量和数据质量，同时自带自动摄像模块可自动拍摄血卡照片并与分析数据同时存储，保证了良好的可追溯性，适合于新生儿筛查等要求高通量和可追溯的应用。详细资料请参考 Prolab DBS System。

联和层析贸易（上海）有限公司是CTC PAL在中国区的总代理商和CTC VAR(Value Added Resellers)的合作伙伴，具有良好的技术经验积累，目前已经与Prolab达成协议，由联和层析贸易（上海）有限公司负责SCAP在中国区的推广、销售和技术服务，欢迎来电咨询。

DBS Integrated Sample Processing

Automated sample processing Advantages
SCAP DBS system components mounted on a robotic platform
Comparison of conventional DBS sample
handling with the SCAP DBS system
Dried blood spot (DBS) technology coupled
to highly sensitive LC-MS/MS systems opens
up new ways in bioanalytics both in the
healthcare and the pharmaceutical industries.
In the healthcare industry, complete measurements
are done to diagnose patients to
determine the efficacy of administered drugs
or to screen for early detection of diseases. In
the pharmaceutical industry, measurements
are done during the development process of
new drugs (e.g. PK/TK studies, etc.).
The major drawback of conventional DBS bioanalytics
is the time consuming, error prone
and labor intensive nature of manual sample
pre-treatment. The SCAP DBS system from
Prolab Instruments represents a unique
approach for direct and automated DBS
analysis and eliminates the drawback of
current methods. The SCAP DBS system fully
automates the DBS cards handling and allows
online sample extraction without the need for
punching of sample cards.

SCAP DBS sample process
The rack with the DBS cards is placed into the
SCAP DBS system. According to the softwaredefined
sample list, the robotic arm transfers
the card into the clamp module where the
DBS card is directly inserted into the HPLC
flow path for online extraction without
punching out any part of the DBS card. The
different adapters available for the SCAP DBS
system allow for extraction of different areas
of the sample spot and seal the DBS card
against pressures of up to 200 bar.