尊敬的会员请选择进入的厂商展位
开通仪会通服务,请联系客服人员
刘老师13717560883(微信同号)
企业微信二维码
仪器信息网 3i讲堂 专家详情
Xiang Zhang, PhD 教授

美国路易斯维尔大学化学系

个人简介:Professor Xiang Zhang received his B.S. in Radiochemistry from Lanzhou University (Lanzhou, China) in 1989 and his M.S. in Nuclear Physics from Institute of Modern Physics, Chinese Academy of Sciences (Lanzhou, China) in 1992. He joined Purdue University (West Lafayette, Indiana) in 1996, and received his Ph.D. degree in Analytical Chemistry in 2001. After his graduation, Dr. Zhang joined Beyond Genomics, Inc., a systems biology company in Boston, to develop bioanalytical and bioinformatics platforms for disease biomarker discovery and validation. In 2004, Dr. Zhang returned to the Purdue University as a Research Assistant Professor and Lead Scientist at the Bindley Bioscience Center, to continue his research foci on biological data management, data integration and data mining for large scale proteomics and metabolomics research. He joined the Department of Chemistry at the University of Louisville (Louisville, Kentucky) as an Associate Professor in 2008 and was promoted to Professor in 2011. Dr. Zhang also serves as an Associate Faculty member of the Department of Pharmacology and Toxicology and the Director of the Center for Regulatory and Environmental Analytical Metabolomics (CREAM) at the University of Louisville. His research centers on molecular systems biology by developing high throughput bioanalytical methods and bioinformatics tools for the analyses of complex mixtures derived from living systems. Dr. Zhang published 198 peer-reviewed papers and book chapters. He also received multiple research awards in his career. 查看更多

正在参与的会议

  • 报名中
    大会报告:Multi-omics studies on metabolism changes in alcohol-associated liver disease 第九届 色谱网络会议(iCC2024)

    2024.08.26 14:00-18:00

    Metabolic dysfunction in the liver represents a predominant feature in the early stages of alcohol-associated liver disease (ALD). However, the mechanisms underlying this are only partially understood. To investigate the metabolic characteristics of the liver in ALD, we quantified polar metabolites and lipids in the liver of mice with experimental ALD using metabolomics and lipidomics. A total of 119 polar metabolites had significant abundance alterations in the livers of alcohol-fed mice. Pathway analysis revealed that amino acid metabolism was the most affected by alcohol in the mouse liver. Metabolites involved in glycolysis and the TCA cycle were decreased, while glycerol 3-phosphate (G3P) and long-chain fatty acids were increased. Lipid quantification unveiled an upregulation of multiple lipid classes, suggesting that alcohol consumption drives metabolism toward lipid synthesis. Results from enzyme expression and activity detection indicated that the decreased activity of mitochondrial glycerol 3-phosphate dehydrogenase (mGPDH) contributed to the disordered metabolism.查看更多
    立即报名
联系我们

会议赞助:13717560883(微信同号)刘老师

扫描二维码联系我

关注微服务 参会不迷路

下载app 回看更便捷