Song Zhao _Frontage Laboratories, Inc_3i讲堂

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Song Zhao Senior Director

Frontage Laboratories, Inc

个人简介:Dr. Song Zhao obtained his phD in bioorganic and analytical chemistry in 2008 from Virginia Tech. Since 2008, he joined PPD at Richmond, VA as senior research scientist dedicated to the method development and method validation for small molecules and biologics using LC-MS platform. Since 2017, Dr. Zhao joined Frontage Laboratories (Shanghai) as director of Biologics and Bioanalytical department supporting dozens of BE/biosimilar studies and new drugs bioanalytical support. Since 2023, he moved back to US to join Frontage Laboratories Exton location and serve as SME (subject Matter Expert) with LC-MS platform. Dr. Zhao is actively involved in professional meetings, such as WRIB, AAPS, ASMS and CBF conferences. He also published several papers in peer reviewed journals. 查看更多

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大会报告：Bioanalytical Strategies for the Quantification of Oligonucleotides in Tissue Samples 第九届色谱网络会议（iCC2024）
2024.08.26 14:00-18:00

Oligonucleotides have emerged as a prominent area in drug development in recent years. However, the bioanalysis of oligonucleotides presents unique challenges, including non-specific binding, high polarity, low sensitivity, stability issues, high matrix effects and variable recovery. Analyzing various tissue samples is crucial to understanding oligonucleotide biodistribution, often necessitating the examination of multiple tissue types. Effectively analyzing these diverse tissue samples poses a significant challenge in oligonucleotide drug development. This talk will address these challenges and propose a generic approach for tissue sample analysis. 查看更多

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