RAN结合蛋白3抗体

Quantity size:

0.2ml

Concentration:

1mg/ml RAN结合蛋白3抗体  Buffer = 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Background:

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds toRAN结合蛋白3抗体 CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.

RAN结合蛋白3抗体Also known as:

Ran BP-3; Ran binding protein 3; Ran-binding protein 3; RANB3_HUMAN; RanBP3.

Specificity:

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Rabbit Polyclonal IgG,RAN结合蛋白3抗体 affinity purified by Protein A.

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Reacts with: Human, Mouse, Rat, Chicken, Dog, Pig, .

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Immunogen: KLH conjugated synthetic peptide derived from human RanBP3.

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Predicted Molecular Weight: 60kDa.

Storage:

RAN结合蛋白3抗体Shipped at 4℃, Store at -20℃ (Avoid repeated freeze/thaw cycles).

Application:

WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500   
Not yet tested in other applications. 
Optimal working dilutions must be determined by the end user.

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