NFKBIB抗原(重组蛋白)
中文名称: NFKBIB抗原(重组蛋白)
英文名称: NFKBIB Antigen (Recombinant Protein)
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述
Fusion protein corresponding to C terminal 250 amino acids of human NFKBIB
技术规格
Full name: | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
Synonyms: | IKBB; TRIP9 |
Swissprot: | Q15653 |
Gene Accession: | BC015528 |
Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: | Escherichia coli |
Tags: | His tag C-Terminus, GST tag N-Terminus |
Background: | The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene. |
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