贝勒医学院全球招聘生命科学、分析化学博士后

　　职位一：贝勒医学院 Xiaosong Wang实验室招聘新一代测序数据分析和综合生物信息学博士后

　　职位发布日期: 2014年6月16日

　　申请截止日期：Open Until Filled

　　主要研究内容：Discover driving genetic aberrations and therapeutic targets in breast cancer from next-generation sequencing data.

　　职位描述:

　　Postdoc position is available at Wang laboratory. The individual will join our integrative bioinformatics initiatives aimed at discovering cancer genes and targets from next generation sequencing and high-throughput genomics data, and will be responsible for the development of novel analyses and bioinformatics tools to analyze whole-genome sequencing and RNAseq data, as well as to integrate other cancer genomics datasets. The main focus of our projects will be discovering driving genetic aberrations and therapeutic targets in breast cancer from next-generation sequencing data. We are looking for highly motivated applicant who has a strong background and hands-on experience in next-generation sequencing data analysis and integrative bioinformatics.

　　Less than 2 years of postdoctoral experience in a related field. Preference will be given to those with additional experience in cancer related research and/or experimental biology.

　　招聘实验室介绍：

　　https://www.bcm.edu/research/centers/breast/wanglab/

　　线上申请：

　　https://www.medschooljobs.org/applicants/jsp/shared/frameset/Frameset.jsp?time=1403582015748

　　职位二：贝勒医学院招聘研究助理

　　职位发布日期: 2014年6月16日

　　申请截止日期：Open Until Filled

　　工作职责：

　　A Research Assistant II position is available at the metabolomics core facility, Alkek Center for Molecular Discovery.

　　*Sample preparation and extraction of metabolites from various complex biological matrices.

　　*Unbiased profiling of metabolome by LC-MS/MS GC-MS analysis.

　　*Quantitation of targeted metabolites by MRM experiments.

　　*Data analysis using various database tools.

　　*Pathway mapping by IPA and OCM software programs.

　　*Run standards and controls, verifying equipment function in order to generate high quality data.

　　*Basic maintenance and trouble shooting of mass spectrometers and HPLCs.

　　*Maintain accurate laboratory notebooks and electronic data records.

　　*Ability to handle multiple projects at once and complete them in a timely manner.

　　*Follow laboratory safety procedures.

　　职位要求：

　　Minimum Education Required: Master's degree in a basic science or equivalent*.

　　MS degree in analytical chemistry preferred.

　　Minimum Job Experience Required: One year of related experience.

　　*NOTE: A Bachelor's degree and two years of directly related experience is considered equivalent to a Master's degree.

　　Experience in sample preparation, small molecule mass spectrometry using triple quadrupole mass spectrometers, developing MRM methods and the data analysis.

　　The ideal candidate should possess exceptional skills in the application LC/MS and GC/MS techniques to investigate the metabolite biomarkers in a variety of biological samples.

　　Good understanding of analytical chemistry and biochemical pathways in relevant disease areas

　　Excellent communications skills and ability to work independently as well as in a team of diverse cultural backgrounds are required.

　　Preference will be given to those who have hand-on experience on UPLC-MS operation, method development, maintenance, sample preparation, drug metabolism, and metabolite identification using MS/MS.

　　Training in pharmacology and toxicology are a plus.

　　Expertise on working with Agilent triple quadrupole LC-MS systems is considered a plus.

　　线上申请：

　　https://www.medschooljobs.org/applicants/jsp/shared/frameset/Frameset.jsp?time=1403588552097