Q-VD-OPh

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产品描述：

产品名称：Q-VD-OPh

描述:

Q-VD-OPh is a potent pan-caspase inhibitor with IC50 ranging from 25 to 400 nM for caspases 1, 3, 8, and 9, showing inhibitory effects on terminal caspase activation, substrate cleavage, and DNA ladder formation associated with apoptosis.

别名: QVD-OPH；Quinoline-Val-Asp-Difluorophenoxymethylketone

CAS号: 1135695-98-5

靶点: Caspase

分子式: C₂₆H₂₅F₂N₃O₆

In vivo(体内研究): Chronic treatment with Q-VD-OPh prevents caspase-7 activation and limits the pathological changes associated with tau, including caspase cleavage. Q-VD-OPh could be a potential therapeutic compound for the treatment of Alzheimer's disease.

分子量: 513.49

纯度: >97%

储存/保存方法: store at -20℃ for one year（Powder）； in DMSO or others solvent store at 2-4℃ for two weeks, at -20℃ for six months.

可溶性/溶解性: Ethanol ：100 mg/mL (194.75 mM)
DMSO : ≥25 mg/mL

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