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当前位置: 爱必信 > 蛋白质/多肽 > Recombinant Mouse IgG2B Fc, 小鼠蛋白IgG2B Fc

Recombinant Mouse IgG2B Fc, 小鼠蛋白IgG2B Fc

供货周期: 一周
品牌: 爱必信
规格: 10ug
货号: abs04690
CAS号:
报价: ¥252
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产品描述:

产品名称:Recombinant Mouse IgG2B Fc

描述: Recombinant Mouse Ig gamma-2B chain C region is produced by our expression system and the target gene encoding Glu97-Lys335 is expressed

氨基酸序列: MSSSVTVPSSTWPSQTVTCSVAHPASSTTVDKKLEPSGPISTINPCPPCKECHKCPAPNLEGGPS VFIFPPNIKDVLMISLTPKVTCVVVDVSEDDPDVRISWFVNNVEVHTAQTQTHREDYNSTIRVVS ALPIQHQDWMSGKEFKCKVNNKDLPSPIERTISKIKGLVRAPQVYILPPPAEQLSRKDVSLTCLV VGFNPGDISVEWTSNGHTEENYKDTAPVLDSDGSYFIYSKLDIKTSKWEKTDSFSCNVRHEGLKN YYLKKTISRSPGK

背景说明: As a monomeric immunoglobulin that is predominately involved in the secondary antibody response and the only isotype that can pass through the human placenta, Immunoglobulin G (IgG) is synthesized and secreted by plasma B cells, and constitutes 75% of serum immunoglobulins in humans. IgG antibodies protect the body against the pathogens by agglutination and immobilization, complement activation, toxin neutralization, as well as the antibody-dependent cell-mediated cytotoxicity (ADCC). IgG tetramer contains two heavy chains (50 kDa ) and two light chains (25 kDa) linked by disulfide bonds, that is the two identical halves form the Y-like shape. IgG is digested by pepsin proteolysis into Fab fragment (antigen-binding fragment) and Fc fragment ("crystallizable" fragment). IgG1 is most abundant in serum among the four IgG subclasses (IgG1, 2, 3 and 4) and binds to Fc receptors (FcγR ) on phagocytic cells with high affinity. Fc fragment is demonstrated to mediate phagocytosis, trigger inflammation, and target Ig to particular tissues. Protein G or Protein A on the surface of certain Staphylococcal and Streptococcal strains specifically binds with the Fc region of IgGs, and has numerous applications in biotechnology as a reagent for affinity purification. Recombinant IgG Fc Region is suggested to represent a potential anti-inflammatory drug for treatment of human autoimmune diseases.

别名: Ig gamma-2 chain C region,IgG2B Fc

Accession: P01867

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04690   Recombinant Mouse IgG2B Fc   10ug   252.00   立即咨询
  abs04690   Recombinant Mouse IgG2B Fc   50ug   756.00   立即咨询
  abs04690   Recombinant Mouse IgG2B Fc   500ug   3822.00   立即咨询
  abs04690   Recombinant Mouse IgG2B Fc   1mg   5200.00   立即咨询

产品更多信息请进入爱必信网站咨询

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爱必信(上海)生物科技有限公司

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信用代码

913101155665500522

成立日期

2010-12-13

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2500

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Recombinant Mouse IgG2B Fc, 小鼠蛋白IgG2B Fc由爱必信(上海)生物科技有限公司为您提供,货号abs04690,规格:10ug,CAS号:,如您想了解更多关于Recombinant Mouse IgG2B Fc, 小鼠蛋白IgG2B Fc价格、Recombinant Mouse IgG2B Fc, 小鼠蛋白IgG2B Fc结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Mouse IgG2B Fc, 小鼠蛋白IgG2B Fc外,还可为您提供DAPI染色液,DAPI Staining Solution,absin品牌、CMV病毒兔多抗,HRP标记、游离DNA提取试剂盒等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,爱必信客户服务电话,售前、售后均可联系。
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