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当前位置: 爱必信 > 蛋白质/多肽 > Recombinant Human Thrombospondin-1/THBS1 (C-10His), 人蛋白Thrombospondin-1/THBS1 (C-10His)

Recombinant Human Thrombospondin-1/THBS1 (C-10His), 人蛋白Thrombospondin-1/THBS1 (C-10His)

供货周期: 一周
品牌: 爱必信
规格: 10ug
货号: abs04665
CAS号:
报价: ¥756
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产品描述:

产品名称:Recombinant Human Thrombospondin-1/THBS1 (C-10His)

背景说明: Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and with the extracellular matrix (ECM). TSP-1 contains an N-terminal Laminin G-like globular domain, an extended central region with one vWFC domain, 3 TSP type 1domains, 2 EGF-like domains, and 8 TSP type3 domains, and a globular TSP C-terminal domain. Distinct regions of TSP-1 have been associated with binding to particular ECM or cellular molecules. TSP-1 counteracts the angiogenic, hypotensive, and antithrombotic effects of nitric oxide (NO). It binds and neutralizes VEGF, blocks VEGF R2 signaling on vascular endothelial cells(EC), and destabilizes adhesive contacts between EC. TSP-1 also plays an important role in wound repair and tissue fibrosis by binding latent TGF-beta and inducing release of the active cytokine from the latency associated peptide (LAP).

描述:

Recombinant Human Thrombospondin-1 is produced by our expression system and the target gene encoding Asn19-Pro1170 is expressed

氨基酸序列: NRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVR AEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALL ATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQ NVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELS SMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQN SVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDS LNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKP CEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTEN QICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHN GEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGH YSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDG IGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACA ADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDID EDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDGDGRGD ACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCD PGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGY SGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRV VMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKYECRDPGGGGSHHHHHHHHHH

别名: Thrombospondin-1; THBS1; TSP; TSP1

Accession: P07996

纯度: Greater than 80% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04665   Recombinant Human Thrombospondin-1/THBS1 (C-10His)   10ug   756.00   立即咨询
  abs04665   Recombinant Human Thrombospondin-1/THBS1 (C-10His)   50ug   2100.00   立即咨询
  abs04665   Recombinant Human Thrombospondin-1/THBS1 (C-10His)   500ug   12936.00   立即咨询
  abs04665   Recombinant Human Thrombospondin-1/THBS1 (C-10His)   1mg   17600.00   立即咨询

产品更多信息请进入爱必信网站咨询

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企业名称

爱必信(上海)生物科技有限公司

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信用代码

913101155665500522

成立日期

2010-12-13

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2500

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Recombinant Human Thrombospondin-1/THBS1 (C-10His), 人蛋白Thrombospondin-1/THBS1 (C-10His)由爱必信(上海)生物科技有限公司为您提供,货号abs04665,规格:10ug,CAS号:,如您想了解更多关于Recombinant Human Thrombospondin-1/THBS1 (C-10His), 人蛋白Thrombospondin-1/THBS1 (C-10His)价格、Recombinant Human Thrombospondin-1/THBS1 (C-10His), 人蛋白Thrombospondin-1/THBS1 (C-10His)结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Human Thrombospondin-1/THBS1 (C-10His), 人蛋白Thrombospondin-1/THBS1 (C-10His)外,还可为您提供胶原酶 I型;蛋白水解酶、游离DNA提取试剂盒、细胞膜荧光探针DiD, DiD细胞膜染料等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,爱必信客户服务电话,售前、售后均可联系。
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