公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 产品描述: 产品名称:Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His) 描述: Recombinant Human CD226 Antigen is produced by our Mammalian expression system and the target gene encoding Glu19-Asn247 is expressed with a 6His tag at the C-terminus. 氨基酸序列: EEVLWHTSVPFAENMSLECVYPSMGILTQVEWFKIGTQQDSIAIFSPTHGMVIRKPYAERVYFLN STMASNNMTLFFRNASEDDVGYYSCSLYTYPQGTWQKVIQVVQSDSFEAAVPSNSHIVSEPGKNV TLTCQPQMTWPVQAVRWEKIQPRQIDLLTYCNLVHGRNFTSKFPRQIVSNCSHGRWSVIVIPDVT VSDSGLYRCYLQASAGENETFVMRLTVAEGKTDNHHHHHH 背景说明: Human DNAX accessory molecule 1 (DNAM-1/CD226) is a 65 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. Mature human DNAM-1 contains an extracellular domain (ECD) with two Ig-like C2-set domains and a cytoplasmic region that contains motifs for binding PDZ domains and band 4.1 family proteins. DNAM-1 is expressed on multiple lymphoid and myeloid cells and interacts with CD155 and CD112. Ligation of DNAM-1 promotes the activation of NK cells, CD8+ T cells, and mast cells, dendritic cell maturation, megakaryocyte and activated platelet adhesion to vascular endothelial cells, and monocyte extravasation; it inhibits the forrmation of osteoclasts. Plateletendothelium, interactions mediated by DNAM-1, enable the metastasis of tumor cells to the lung. 别名: CD226 antigen; DNAX accessory molecule 1; DNAM-1; CD226; DNAM1 Accession: Q15762 纯度: Greater than 95% as determined by reducing SDS-PAGE. 来源: Human Cells 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. 产品信息订购:
产品货号 |
产品名称 |
规格 |
价格 |
大包装及货期 |
abs04652 |
Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His) |
10ug |
630.00 |
立即咨询 |
abs04652 |
Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His) |
50ug |
1890.00 |
立即咨询 |
abs04652 |
Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His) |
500ug |
7560.00 |
立即咨询 |
abs04652 |
Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His) |
1mg |
10000.00 |
立即咨询 |
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