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当前位置: 爱必信 > 蛋白质/多肽 > Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc), 人蛋白TNF Receptor Superfamily Member 11B/OPG (C-Fc)

Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc), 人蛋白TNF Receptor Superfamily Member 11B/OPG (C-Fc)

供货周期: 7天
品牌: 爱必信
型号: 10ug
货号: abs04629
报价: ¥1260
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产品描述:

产品名称:Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc)

背景说明: TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNFRSF11B can reduce the production of osteoclasts by inhibiting the differentiation of osteoclast precursors into osteoclasts and also regulates the resorption of osteoclasts in vitroand in vivo. TNFRSF11B binding to RANKL on osteoblast/stromal cells, blocks the RANKL-RANK ligand interaction between osteoblast/stromal cells and osteoclast precursors. This has the effect of inhibiting the differentiation of the osteoclast precursor into a mature osteoclast.

描述: Recombinant Human Osteoprotegerin is produced by our Mammalian expression system and the target gene encoding Glu22-Leu201 is expressed with a Fc tag at the C-terminus.

氨基酸序列: ETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPV CKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPDGFFS NETSSKAPCRKHTNCSVFGLLLTQKGNATHDNICSGNSESTQKCGIDVTLDIEGRMDPKSCDKTH TCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKT KPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPS RDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQ GNVFSCSVMHEALHNHYTQKSLSLSPGK

别名: Tumor necrosis factor receptor superfamily member 11B; Osteoclastogenesis inhibitory factor; Osteoprotegerin; TNFRSF11B; OCIF; OPG

Accession: O00300

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Human Cells

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

产品信息订购:

  产品货号   产品名称   规格 价格 大包装及货期
  abs04629   Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc)   10ug   1260.00   立即咨询
  abs04629   Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc)   50ug   3696.00   立即咨询
  abs04629   Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc)   500ug   14112.00   立即咨询
  abs04629   Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc)   1mg   19200.00   立即咨询

产品更多信息请进入爱必信网站咨询

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企业名称

爱必信(上海)生物科技有限公司

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企业类型

信用代码

913101155665500522

成立日期

2010-12-13

注册资本

2500

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Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc), 人蛋白TNF Receptor Superfamily Member 11B/OPG (C-Fc)由爱必信(上海)生物科技有限公司为您提供,货号abs04629,规格:10ug,CAS号:,如您想了解更多关于Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc), 人蛋白TNF Receptor Superfamily Member 11B/OPG (C-Fc)价格、Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc), 人蛋白TNF Receptor Superfamily Member 11B/OPG (C-Fc)结构式、批发、用途等信息,欢迎咨询。除供应Recombinant Human TNF Receptor Superfamily Member 11B/OPG (C-Fc), 人蛋白TNF Receptor Superfamily Member 11B/OPG (C-Fc)外,还可为您提供胰蛋白酶-EDTA消化液(0.25%) 不含酚红、重组人胰岛素Insulin,absin品牌、DAPI染色液,DAPI Staining Solution,absin品牌等试剂,公司有专业的客户服务团队,是您值得信赖的合作伙伴,爱必信客户服务电话,售前、售后均可联系。
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