公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 产品描述: 产品名称:Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His) 背景说明: Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of c-fms proto-oncogene) were initially implicated as essential for normal monocyte development as well as for trophoblastic implantation. It plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. It is required for normal male and female fertility, and for normal development of milk ducts and acinar structures in the mammary gland during pregnancy. Aberrant expression of CSF1 or CSF1R may play a role in inflammatory diseases, such as rheumatoid arthritis, glomerulonephritis, atherosclerosis, and allograft rejection. 描述: Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor is produced by our Mammalian expression system and the target gene encoding Ile20-Pro517 is expressed with a 6His tag at the C-terminus. 氨基酸序列: IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSILSTNNATFQNTGTYRC TEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFEDQDALLPCLLTDPVLEAGVSLVRVRGRPLM RHTNYSFSPWHGFTIHRAKFIQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVR IRGEAAQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVDFQHAGNYSCV ASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGLNLKVMVEAYPGLQGFNWTYLGPFSD HQPEPKLANATTKDTYRHTFTLSLPRLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWT FINGSGTLLCAASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQSLLTV ETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDEFLFTPHHHHHH 别名: Macrophage colony-stimulating factor 1 receptor; CSF-1 receptor; CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD115; CSF1R; FMS Accession: P07333 纯度: Greater than 95% as determined by reducing SDS-PAGE. 来源: Human Cells 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. 溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 产品信息订购:
产品货号 |
产品名称 |
规格 |
价格 |
大包装及货期 |
abs04561 |
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His) |
10ug |
420.00 |
立即咨询 |
abs04561 |
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His) |
50ug |
882.00 |
立即咨询 |
abs04561 |
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His) |
500ug |
5040.00 |
立即咨询 |
abs04561 |
Recombinant Human Macrophage Colony-stimulating Factor 1 Receptor/M-CSF R/CSF1R/CD115(C-6His) |
1mg |
7600.00 |
立即咨询 |
产品更多信息请进入爱必信网站咨询
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