公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 产品描述: 产品名称:Recombinant Cynomolgus B7-1/CD80 (C-6His) 描述: Recombinant Cynomolgus monkey T-lymphocyte Activation Antigen CD80 is produced by our Mammalian expression system and the target gene encoding Val35-Asn242 is expressed with a 6His tag at the C-terminus. 氨基酸序列: VIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNL SIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVMLSVKADFPTPSITDFEIPPSNIRRIICST SGGFPEPHLSWLENGEELNAISTTVSQDPETELYTVSSKLDFNMTTNHSFMCLIKYGHLRVNQTF NWNTPKQEHFPDNHHHHHH 背景说明: Cynomolgus Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells.CD80 plays key, yet distinct roles in the activation of T cells. B7-1/CD80 and B7-2/CD86, together with their receptors CD28 and CTLA4, constitute one of the dominant co-stimulatory pathways that regulate T- and B- cell responses. CD80 is mostly expressed on the surface of antigen-presenting cells including activated B cells, macrophages and dendritic cells. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down-regulation of the immune response. CD80 is thus regarded as promising therapeutic targets for autoimmune diseases and various carcinomas. 别名: T-lymphocyte activation antigen CD80; Activation B7-1 antigen; B7; CD80 Accession: G7MKE2 纯度: Greater than 95% as determined by reducing SDS-PAGE. 来源: Escherichia coli. 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. 溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 产品信息订购:
产品货号 |
产品名称 |
规格 |
价格 |
大包装及货期 |
abs04555 |
Recombinant Cynomolgus B7-1/CD80 (C-6His) |
10ug |
420.00 |
立即咨询 |
abs04555 |
Recombinant Cynomolgus B7-1/CD80 (C-6His) |
50ug |
756.00 |
立即咨询 |
abs04555 |
Recombinant Cynomolgus B7-1/CD80 (C-6His) |
500ug |
5040.00 |
立即咨询 |
abs04555 |
Recombinant Cynomolgus B7-1/CD80 (C-6His) |
1mg |
7600.00 |
立即咨询 |
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