Recombinant Mouse Complement Component C3a/C3a, 小鼠蛋白Complement Component C3a/C3a

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产品描述：

产品名称：Recombinant Mouse Complement Component C3a/C3a

描述: Recombinant Mouse Complement Component C3a is produced by our E.coli expression system and the target gene encoding Ser671-Arg748 is expressed.

氨基酸序列: SVQLMERRMDKAGQYTDKGLRKCCEDGMRDIPMRYSCQRRARLITQGENCIKAFIDCCNHITKLR EQHRRDHVLGLAR

背景说明: Complement is defined as key part of innate immunity and as the first line of defense in the fight against invading pathogens. Complement 3 (C3) is the most abundant component of the complement cascade and the convergent point for all three major complement activation pathways: namely classical, alternative and mannose-binding lectin pathways. Complement activation leads to the formation of the C3 convertase, which cleaves C3 into the key effector molecules, C3a (anaphylatoxin) and C3b (opsonin) which then drive microbe removal. By binding to C3a receptor (C3aR), C3a exhibits potent anaphylatoxin activity, including increased vascular permeability, triggering degranulation of mast cells, inflammation, and activating leukocytes.

别名: Complement Component C3a, Anaphylatoxin, C3a

Accession: P01027

纯度: Greater than 95% as determined by reducing SDS-PAGE.

来源: Escherichia coli.

内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.

溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

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