公告提醒:爱必信所有产品和服务仅用于科学研究,不用于临床应用及其他用途提供产品和服务(也不为任何个人提供产品和服务)! 产品描述: 产品名称:Recombinant Mouse OX40/TNFRSF4/CD134 (C-Fc) 描述: Recombinant Mouse OX40 is produced by our Mammalian expression system and the target gene encoding Val20-Pro211 is expressed with a Fc tag at the C-terminus. 氨基酸序列: VTARRLNCVKHTYPSGHKCCRECQPGHGMVSRCDHTRDTLCHPCETGFYNEAVNYDTCKQCTQCN HRSGSELKQNCTPTQDTVCRCRPGTQPRQDSGYKLGVDCVPCPPGHFSPGNNQACKPWTNCTLSG KQTRHPASDSLDAVCEDRSLLATLLWETQRPTFRPTTVQSTTVWPRTSELPSPPTLVTPEGPDIE GRMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNW YVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQ PREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLY SKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK 背景说明: OX40, also termed CD134 and TNFRSF4, is a T cell co-stimulatory molecule of the TNF receptor superfamily which plays a key role in the survival and homeostasis of effector and memory T cells. OX40 is expressed on CD4+ and CD8+ T cells upon engagement of the TCR by antigen presenting cells along with co-stimulation by CD40-CD40 Ligand and CD28-B7. The interaction between OX40 and OX40 ligand (OX40L) will occur when activated T cells bind to professional antigen-presenting cells (APCs). The T-cell functions, including cytokine production, expansion, and survival, are then enhanced by the OX40 costimulatory signals. OX40 signals are critical for controlling the function and differentiation of Foxp3+ regulatory T cells. OX40-OX40L interaction regulates T-cell tolerance, peripheral T-cell homeostasis, and T-cell-mediated inflammatory diseases. 别名: Tumor necrosis factor receptor superfamily member 4,Tnfrsf4,OX40,CD134,Txgp1, REF: C1124 Accession: P47741 纯度: Greater than 95% as determined by reducing SDS-PAGE. 来源: Human Cells 内毒素水平: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. 活性: Measured by its ability to bind Mouse TNFSF4 in functional ELISA. The ED50 for this effect is typically 4.2 ug/mL. 溶解方法: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 形态: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. 储存/保存方法: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. 产品信息订购:
产品货号 |
产品名称 |
规格 |
价格 |
大包装及货期 |
abs04274 |
Recombinant Mouse OX40/TNFRSF4/CD134 (C-Fc) |
10ug |
798.00 |
立即咨询 |
abs04274 |
Recombinant Mouse OX40/TNFRSF4/CD134 (C-Fc) |
50ug |
2100.00 |
立即咨询 |
abs04274 |
Recombinant Mouse OX40/TNFRSF4/CD134 (C-Fc) |
500ug |
12936.00 |
立即咨询 |
abs04274 |
Recombinant Mouse OX40/TNFRSF4/CD134 (C-Fc) |
1mg |
17600.00 |
立即咨询 |
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