Monosodium urate (crystals)

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试剂描述：

产品名称：Monosodium urate (crystals)

产品别名：Uric acid monosodium salt (crystals)

CAS号：1198-77-2

英文别名：Monosodium urate (crystals)

分子量：190.10

分子式：C₅H₃N₄O₃?Na

纯度：

外观：见爱必信官网

保存方法：Store at -20° C

描述：

Monosodium urate has been reported to be an inflammatory compound. Mechanistic studies suggest that this compound intracellularly engages caspase-1-activating cryopyrin inflammasome, resulting in the production of active IL-1β and IL-18. Experiments have shown that monosodium urate crystals also induce triggering receptor expressed on myeloid cells 1 (TREM-1) expression in infiltrating leukocytes in a murine air-pouch model of crystal-induced acute inflammation. Monosodium urate is also an activator of cryopyrin.

应用：A Cryopyrin inflammatory compound that induces IL-1β production

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