Iberiotoxin

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试剂描述：

产品名称：Iberiotoxin

产品别名：IbTX; IBERIOTOXIN SCORPION BUTHUS TAMULUS

CAS号：129203-60-7

英文别名：Iberiotoxin

分子量：4230.85

分子式：C₁₇₉H₂₇₄N₅₀O₅₅S₇

纯度：≥95%

外观：见爱必信官网

保存方法：Store at -20℃,1 year.

描述：

Iberotoxin is a highly selective and potent blocker of the MaxiK (high conductance Ca²⁺ activated K⁺ channels) that does not affect other types of voltage-dependent K⁺ channels. Because of iberiotoxin's strong ability to block Ca²⁺ activated K⁺ channels, in mammalian motor nerve terminals the compound can induce dihydropyridine sensitive release of ACh. In rat organotypic dorsal striatal slices iberiotoxin and margatoxin were both observed to induce production of c-fos like mRNA and protein. Iberiotoxin is an inhibitor of MaxiKα.

应用：A highly selective and potent high conductance Ca²⁺-activated K⁺ channel blocker

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