Two identical illumination arms

Chromatic correction from 440 to 660 nm

Light-sheet generation by beam scanning

Variable light-sheet thickness (optional)

Water-dipping objective lenses (see below)

Two identical detection arms

Water-dipping objective lenses (see below)

Fast filter wheels with 10 positions and 50 ms between adjacent positions

Filters adapted to the selected laser lines

Variable magnification (optional)

High-speed sCMOS cameras Hamamatsu Orca Flash 4.0 with 2048 x 2048 pixels of 6.5 μm x 6.5 μm size

High precision mounting unit

Fast exchange of the unit with high precision

Mounting chamber with temperature control (see below)

2 x Nikon CFI Plan Fluor 10XW 0.3 NA water immersion for illumination

2 x Nikon CFI Apo LWD 25XW 1.1 NA water immersion for detection

Other objective lenses on request

Water-sealed inert PEEK plastic chamber, autoclavable and biocompatible

Sample supported from below for improved stability

Easy access from above for sample mounting, injections, etc.

Fast and precise temperature control, range 15-40°C

High-precision XYZ and fast rotation stage

XYZ piezo crawler stage with 100 nm resolution and 8.5 mm (X) and 1.2 mm (YZ) travel range for fast sample positioning and stack acquisition

Custom-made rotation stage with > 360 degrees/second speed

All electronic components included in the microscope housing

Embedded microscope software with open communication interface

Open GUI control for interactive control and microscope automation

Computer with 64 GB RAM, Intel Dual Six Core CPU

High-speed RAID controller for data streaming

8 x 4 TB local storage in RAID 0

One 40 inch monitor