骨形态发生蛋白7抗体elisa实验

骨形态发生蛋白7抗体英文名称  Anti-BMP7 

中文名称  骨形态发生蛋白7抗体 

别    名  bone morphogenetic protein 7 precursor; osteogenic protein 1; BMP-7; OP-1; BMP 7; Bone morphogenic protein 7; Eptotermin alfa; OP 1; OP1 

浓    度  1mg/1ml 

规 格  0.1ml/100μg  0.2ml/200μg 

抗体来源  Rabbit  

骨形态发生蛋白7抗体克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep   

产品类型  一抗    

研究领域  肿瘤 细胞生物 免疫学 细胞凋亡 生长因子和激素 转录调节因子  

蛋白分子量  predicted molecular weight: 15.7/47kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human BMP7 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq].

Function : Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Subunit : Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with TWSG1.

骨形态发生蛋白7抗体Subcellular Location : Secreted.

Tissue Specificity : Expressed in the kidney and bladder. Lower levels seen in the brain.

Post-translational modifications : Several N-termini starting at positions 293, 300, 315 and 316 have been identified by direct sequencing resulting in secretion of different mature forms (PubMed:17977014).

Similarity : Belongs to the TGF-beta family.

Database links : UniProtKB/Swiss-Prot: P18075.1

骨形态发生蛋白7（BMP-7）是转化生长因子β超家族成员,参与器官发生,细胞增殖、分化及凋亡等.