凯尔血型糖蛋白CD238抗体elisa实验

凯尔血型糖蛋白CD238抗体英文名称  Anti-Blood Group Kell Antigen/CD238 

中文名称  凯尔血型糖蛋白CD238抗体 

别    名  CD238; CD238 antigen; ECE3; kel; Kell blood group; Kell blood group glycoprotein; Kell blood group metallo endopeptidase; Kell blood group metalloendopeptidase; KELL NULL; Kell protein; KELL_HUMAN. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg   

凯尔血型糖蛋白CD238抗体抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Rabbit   

产品类型  一抗    

研究领域  心血管 细胞生物  

蛋白分子量  predicted molecular weight: 83kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human Blood Group Kell Antigen (101-200aa) 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases.

Function : Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.

Subunit : Heterodimer with XK; disulfide-linked.

Subcellular Location : Cell membrane; Single-pass type II membrane protein. Note=Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton. 

凯尔血型糖蛋白CD238抗体Tissue Specificity : Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.

Post-translational modifications : N-glycosylated.

Similarity : Belongs to the peptidase M13 family.

Database links : UniProtKB/Swiss-Prot: P23276.2