卵黄状黄斑病蛋白3抗体elisa实验

卵黄状黄斑病蛋白3抗体英文名称  Anti-Bestrophin 3 

中文名称  卵黄状黄斑病蛋白3抗体 

别    名  Vitelliform macular dystrophy 2 like protein 3; BEST 3; BEST3; BEST3_HUMAN; Bestrophin-3; Bestrophin3; Vitelliform macular dystrophy 2 like 3; Vitelliform macular dystrophy 2-like protein 3; VMD2L3. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg   

抗体来源  Rabbit  

卵黄状黄斑病蛋白3抗体克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Pig, Horse  

产品类型  一抗    

研究领域  肿瘤 信号转导 通道蛋白  

蛋白分子量  predicted molecular weight: 76kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human Bestrophin 3 (45-92aa) 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 

产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Bestrophin-3 is a 668 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (arg-phe-pro) motif and they function as anion channels. Expressed predominantly in skeletal muscle but also found in spinal cord, brain, testis, thymus, retina and bone marrow, Bestrophin-3 forms calcium-sensitive chloride channels. In addition, Bestrophin-3 contains an AI (auto-inhibitory) domain that is capable of regulating the anion channel activity. Due to alternative splicing events, three isoforms exist for Bestrophin-3.

卵黄状黄斑病蛋白3抗体Function : Forms calcium-sensitive chloride channels. Permeable to bicarbonate.

Subcellular Location : Cell membrane.

Tissue Specificity : Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina.

Similarity : Belongs to the bestrophin family.

Database links : UniProtKB/Swiss-Prot: Q8N1M1.1