离子转运相关蛋白SLC7A9抗体elisa实验

英文名称  Anti-SLC7A9 

中文名称  离子转运相关蛋白SLC7A9抗体 

 离子转运相关蛋白SLC7A9抗体别    名  B(0+) type amino acid transporter 1; BAT1; CSNU3; Glycoprotein associated amino acid transporter b0+AT1; Solute carrier family 7 (cationic amino acid transporter y+ system) member 9; BAT1_HUMAN; B(0,+)-type amino acid transporter 1; B(0,+)AT; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9. 

浓    度  1mg/1ml 

规 格  0.2ml/200μg 

抗体来源  Rabbit  

克隆类型  polyclonal 

交叉反应  Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit 

产品类型  一抗    

研究领域  免疫学 通道蛋白 转运蛋白 交换蛋白  

蛋白分子量  predicted molecular weight: 53kDa 

性    状  Lyophilized or Liquid 

免 疫 原  KLH conjugated synthetic peptide derived from human SLC7A9 

亚    型  IgG 

纯化方法  affinity purified by Protein A 

储 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide 

产品应用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  ICC=1:100-500  IF=1:100-500 

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

 离子转运相关蛋白SLC7A9抗体保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 SLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases.

Function : Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.

Subunit : Disulfide-linked heterodimer with the amino acid transport protein SLC3A1.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : Kidney, small intestine, liver and placenta.

 离子转运相关蛋白SLC7A9抗体Similarity : Belongs to the amino acid-polyamine-organocation (APC) superfamily.

Database links : UniProtKB/Swiss-Prot: P82251.1

SLC7A9蛋白Ⅰ型胱氨酸尿石症有一定的关联，该蛋白不但在肾表达，在、小肠等有也有表达。