Hydroxy Tolbutamide

Chemical Name:   Hydroxy Tolbutamide

Catalogue Number:   H969850

Synonyms:   N-(Butylamnocarbonyl)-4-hydroxymethylbenzenesulfonamide; Hydroxytolbutamide; Hydroxymethylcarbutamide; 1-Butyl-3-(p-hydroxymethylphenyl)sulfonylurea;

CAS Number:   5719-85-7

Possible CAS Number:   NA

Mol. Formula:   C12H18N2O4S

Appearance:   White Solid

Melting Point:   101-103°C

Mol. Weight:   286.35

Storage:   -20°C Freezer

Stability:   No Data Available

Solubility:   DMSO, Methanol

Boiling Point:   No Data Available

Category:   Metabolites & Impurities

Applications:   A metabolite of Tolbutamide. Formed by the cytochrome CYP2CIIC8 and IIC9 subfamily of P450 enzymes.

References:   Relling, etl al.: J. Pharmacol. Exp. Ther., 252, 442 (1990), Parent, et al.: J. Pharmacol. Exp. Ther., 261, 780 (1992), Ho, et al.: Life Sci., 52, 21 (1993),