跨膜蛋白KREMEN2抗体

英文名称    KREMEN2    

中文名称    跨膜蛋白KREMEN2抗体    

别    名    Dickkopf receptor 2; KREM2_HUMAN; KREMEN 2; Kremen protein 2; Kremen protein 2 precursor; Kremen2; Kringle containing protein marking the eye and the nose; Kringle containing transmembrane protein 2; Kringle domain containing transmembrane protein 2; Kringle domain-containing transmembrane protein 2; Kringle-containing protein marking the eye and the nose; KRM 2; KRM2; MGC10791; MGC16709.    

跨膜蛋白KREMEN2抗体        

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  细胞类型标志物  细胞膜蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    46kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human KREMEN2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

  跨膜蛋白KREMEN2抗体 产品介绍    background:
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Function:
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling. Forms a ternary complex with Dkk1 and LRP6 and induces rapid endocytosis and removal of the Wnt receptor LRP6 from the plasma membrane.

Subcellular Location:
Membrane.

Similarity:
Contains 1 CUB domain.
Contains 1 kringle domain.
Contains 1 WSC domain.

Gene ID:
79412

Database links:

Entrez Gene: 79412 Human

Entrez Gene: 73016 Mouse

Entrez Gene: 287102 Rat

Omim: 609899 Human

SwissProt: Q8NCW0 Human

SwissProt: Q8K1S7 Mouse

Unigene: 661128 Human

Unigene: 221319 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

  跨膜蛋白KREMEN2抗体 

hz-0368R-FIThz Rabbit Anti-mouse IgM/FITC  FITC标记的兔抗小鼠IgM

hz-0330R-FIThz Rabbit anti-mouse Kappa light chain/FITC  FITC标记的兔抗小鼠k链

hz-0330R-AP Rabbit anti-mouse Kappa light chain/AP  碱性磷酸酶（AP）标记的兔抗小鼠k链

hz-0330R-RBIThz Rabbit anti-mouse Kappa light chain/RBITC  罗丹明标记的兔抗小鼠k链

hz-0330R-Gold Rabbit anti-mouse Kappa light chain/Gold  胶体金标记的兔抗小鼠k链

hz-0330R-HRP Rabbit anti-mouse Kappa light chain/HRP  辣根过氧化物酶标记的兔抗小鼠k链

hz-0330R-Bio Rabbit anti-mouse Kappa light chain/Bio  生物素标记的兔抗小鼠k链

hz-0330R-hzy3 Rabbit anti-mouse Kappa light chain/Cy3  Cy3标记的兔抗小鼠k链

hz-0330R-hzy5 Rabbit anti-mouse Kappa light chain/Cy5  Cy5标记的兔抗小鼠k链

hz-0330R-hzy5.5 Rabbit anti-mouse Kappa light chain/Cy5.5  Cy5.5标记的兔抗小鼠k链

hz-0330R-hzy7 Rabbit anti-mouse Kappa light chain/Cy7  Cy7标记的兔抗小鼠k链

hz-0330R-PE Rabbit anti-mouse Kappa light chain/PE  PE标记的兔抗小鼠k链

hz-0330R-PE-hzy3 Rabbit anti-mouse Kappa light chain/PE-Cy3  PE-Cy3标记的兔抗小鼠k链

hz-0330R-PE-hzY5 Rabbit anti-mouse Kappa light chain/PE-CY5  PE-CY5标记的兔抗小鼠k链

hz-0330R-APhz Rabbit anti-mouse Kappa light chain/APC  APC标记的兔抗小鼠k链

hz-0330R-AF350 Rabbit anti-mouse Kappa light chain/Alexa Fluor 350  Alexa Fluor 350标记的兔抗小鼠k链

hz-0330R-AF488 Rabbit anti-mouse Kappa light chain/Alexa Fluor 488  Alexa Fluor 488标记的兔抗小鼠k链

hz-0330R-AF555 Rabbit anti-mouse Kappa light chain/Alexa Fluor 555  Alexa Fluor 555标记的兔抗小鼠k链

hz-0330R-AF647 Rabbit anti-mouse Kappa light chain/Alexa Fluor 647  Alexa Fluor 647标记的兔抗小鼠k链

hz-0330R-PE-hzy5.5 Rabbit anti-mouse Kappa light chain/PE-Cy5.5  PE-Cy5.5标记的兔抗小鼠k链

hz-0330R-PE-hzy7 Rabbit anti-mouse Kappa light chain/PE-Cy7  PE-Cy7标记的兔抗小鼠k链

hz-0293R-Bio Rabbit Anti-rat IgG/Bio  生物素标记的兔抗大鼠IgG

hz-0293R-HRP Rabbit Anti-rat IgG/HRP  辣根过氧化物酶标记的兔抗大鼠IgG

hz-0293R-RBIThz Rabbit Anti-rat IgG/RBITC  罗丹明标记的兔抗大鼠IgG

hz-0293R-FIThz Rabbit Anti-rat IgG/FITC  FITC标记的兔抗大鼠IgG

hz-0293R-AF350 Rabbit Anti-rat IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗大鼠IgG

hz-0293R-AF488 Rabbit Anti-rat IgG/Alexa Fluor 488  Alexa Fluor 488标记的兔抗大鼠IgG

hz-0293R-Gold Rabbit Anti-rat IgG/Gold  胶体金标记的兔抗大鼠IgG

hz-0293R-AP Rabbit Anti-rat IgG/AP  碱性磷酸酶（AP）标记的兔抗大鼠IgG

hz-0293R-hzy3 Rabbit Anti-rat IgG/Cy3  Cy3标记的兔抗大鼠IgG

hz-0293R-hzy5 Rabbit Anti-rat IgG/Cy5  Cy5标记的兔抗大鼠IgG

hz-0293R-hzy5.5 Rabbit Anti-rat IgG/Cy5.5  Cy5.5标记的兔抗大鼠IgG

hz-0293R-hzy7 Rabbit Anti-rat IgG/Cy7  Cy7标记的兔抗大鼠IgG