生物钟蛋白3抗体

英文名称    PER-3    

中文名称    生物钟蛋白3抗体    

别    名    2810049O06Rik; Cell growth inhibiting gene 13 protein; Cell growth-inhibiting gene 13 protein; Circadian clock protein PERIOD 3; GIG13; gPER3; HGNC:8847; hPER3; mPer3; Per3; PER3_HUMAN; Period circadian protein homolog 3; Period homolog 3 (Drosophila); Period homolog 3; Period homolog 3, Drosophila; Period3.    

生物钟蛋白3抗体        

说 明 书    0.1ml  0.2ml      

研究领域    心血管  细胞生物  细胞周期蛋白  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    132kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human PER-3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

生物钟蛋白3抗体 产品介绍    background:
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. [provided by RefSeq, Jul 2008]

Function:
Component of the circadian clock mechanism which is essential for generating circadian rhythms. Can bind heme.

Subcellular Location:
Cytoplasm. Nucleus. Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS.

Post-translational modifications:
Phosphorylation appears to require association with PER1 and translocation to the nucleus.
Ubiquitinated.

Similarity:
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 2 PAS (PER-ARNT-SIM) domains.

Gene ID:
8863

Database links:

Entrez Gene: 8863 Human

Entrez Gene: 18628 Mouse

Entrez Gene: 78962 Rat

Omim: 603427 Human

SwissProt: P56645 Human

SwissProt: O70361 Mouse

SwissProt: Q8CJE2 Rat

Unigene: 162200 Human

Unigene: 121361 Mouse

Unigene: 230006 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

生物钟蛋白3抗体 

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hz-0375R-hzy7 Rabbit Anti-Guinea pig IgM/Cy7  Cy7标记的兔抗豚鼠IgM

hz-0375R-PE Rabbit Anti-Guinea pig IgM/PE  PE标记的兔抗豚鼠IgM

hz-0375R-PE-hzy3 Rabbit Anti-Guinea pig IgM/PE-Cy3  PE-Cy3标记的兔抗豚鼠IgM

hz-0375R-RBIThz Rabbit Anti-Guinea pig IgM/RBITC  罗丹明标记的兔抗豚鼠IgM

hz-0375R-FIThz Rabbit Anti-Guinea pig IgM/FITC  FITC标记的兔抗豚鼠IgM

hz-0308R-FIThz Rabbit Anti-horse IgG/FITC  FITC标记的兔抗马IgG

hz-0308R-Gold Rabbit Anti-horse IgG/Gold  胶体金标记的兔抗马IgG

hz-0308R-RBIThz Rabbit Anti-horse IgG/RBITC  罗丹明标记的兔抗马IgG

hz-0308R-hzy3 Rabbit Anti-horse IgG/Cy3  Cy3标记的兔抗马IgG

hz-0308R-hzy5 Rabbit Anti-horse IgG/Cy5  Cy5标记的兔抗马IgG

hz-0308R-hzy5.5 Rabbit Anti-horse IgG/Cy5.5  Cy5.5标记的兔抗马IgG

hz-0308R-hzy7 Rabbit Anti-horse IgG/Cy7  Cy7标记的兔抗马IgG

hz-0308R-PE Rabbit Anti-horse IgG/PE  PE标记的兔抗马IgG

hz-0308R-PE-hzy3 Rabbit Anti-horse IgG/PE-Cy3  PE-Cy3标记的兔抗马IgG

hz-0308R-PE-hzY5 Rabbit Anti-horse IgG/PE-CY5  PE-CY5标记的兔抗马IgG

hz-0308R-APhz Rabbit Anti-horse IgG/APC  APC标记的兔抗马IgG

hz-0308R-AF350 Rabbit Anti-horse IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗马IgG

hz-0308R-AF488 Rabbit Anti-horse IgG/Alexa Fluor 488  Alexa Fluor 488标记的兔抗马IgG

hz-0308R-AF555 Rabbit Anti-horse IgG/Alexa Fluor 555  Alexa Fluor 555标记的兔抗马IgG

hz-0308R-AF647 Rabbit Anti-horse IgG/Alexa Fluor 647  Alexa Fluor 647标记的兔抗马IgG

hz-0308R-PE-hzy5.5 Rabbit Anti-horse IgG/PE-Cy5.5  PE-Cy5.5标记的兔抗马IgG

hz-0308R-PE-hzy7 Rabbit Anti-horse IgG/PE-Cy7  PE-Cy7标记的兔抗马IgG

hz-0308R-AP Rabbit Anti-horse IgG/AP  碱性磷酸酶（AP）标记的兔抗马IgG

hz-0308R-HRP Rabbit Anti-horse IgG/HRP  辣根过氧化物酶标记的兔抗马IgG

hz-0308R-Bio Rabbit Anti-horse IgG/Bio  生物素标记的兔抗马IgG

hz-0297R-Bio Rabbit Anti-human IgG/Bio  生物素标记的兔抗人IgG

hz-0297R-AP Rabbit Anti-human IgG/AP  碱性磷酸酶（AP）标记的兔抗人IgG

hz-0297R-HRP Rabbit Anti-human IgG/HRP  辣根过氧化物酶标记的兔抗人IgG

hz-0297R-hzy3 Rabbit Anti-human IgG/Cy3  Cy3标记的兔抗人IgG

hz-0297R-hzy5 Rabbit Anti-human IgG/Cy5  Cy5标记的兔抗人IgG

hz-0297R-PE Rabbit Anti-human IgG/PE  PE标记的兔抗人IgG

hz-0297R-PE-hzy3 Rabbit Anti-human IgG/PE-Cy3  PE-Cy3标记的兔抗人IgG

hz-0297R-PE-hzY5 Rabbit Anti-human IgG/PE-CY5  PE-CY5标记的兔抗人IgG

hz-0297R-APhz Rabbit Anti-human IgG/APC  APC标记的兔抗人IgG

hz-0297R-AF350 Rabbit Anti-human IgG/Alexa Fluor 350  Alexa Fluor 350标记的兔抗人IgG