细胞表面蛋白CD232抗体

英文名称    PLXNC1/CD232    

中文名称    细胞表面蛋白CD232抗体    

别    名    CD232; Plexin-C1; PLXC1_HUMAN; Plxnc1; Virus-encoded semaphorin protein receptor.    

细胞表面蛋白CD232抗体       

说 明 书    0.2ml      

研究领域    细胞生物  神经生物学  细胞膜受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    172kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human PLXNC1/CD232    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 细胞表面蛋白CD232抗体产品介绍    background:
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]

Function:
Receptor for SEMA7A, for smallpox semaphorin A39R, vaccinia virus semaphorin A39R and for herpesvirus Sema protein. Binding of semaphorins triggers cellular responses leading to the rearrangement of the cytoskeleton and to secretion of IL6 and IL8.

Subcellular Location:
Membrane.

Tissue Specificity:
Detected in heart, brain, lung, spleen and placenta.

Post-translational modifications:
N-glycosylated.

Similarity:
Belongs to the plexin family.
Contains 1 Sema domain.

Gene ID:
10154

Database links:

Entrez Gene: 10154 Human

Entrez Gene: 54712 Mouse

Omim: 604259 Human

SwissProt: O60486 Human

SwissProt: Q9QZC2 Mouse

Unigene: 584845 Human

Unigene: 256712 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

细胞表面蛋白CD232抗体

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