肌动蛋白相关蛋白2/3复合物亚基3抗体

英文名称    p21-ARC    

中文名称    肌动蛋白相关蛋白2/3复合物亚基3抗体    

别    名    Actin related protein 2/3 complex subunit 3; ARC21; ARPC3_HUMAN; ARP2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21; ARPC3.    

肌动蛋白相关蛋白2/3复合物亚基3抗体        

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Cow, Rabbit, Xenopus laevis    

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    20kDa    

细胞定位    细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human p21-ARC    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

肌动蛋白相关蛋白2/3复合物亚基3抗体产品介绍    background:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Function:
p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004). 

Subunit:
Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and 

Subcellular Location:
Cytoplasm, cytoskeleton. Cell projection.

Similarity:
Belongs to the ARPC3 family.

Gene ID:
10094

Database links:

Entrez Gene: 10094 Human

Entrez Gene: 56378 Mouse

Entrez Gene: 288669 Rat

Entrez Gene: 415204 Zebrafish

Omim: 604225 Human

SwissProt: O15145 Human

SwissProt: Q9JM76 Mouse

Unigene: 524741 Human

Unigene: 275942 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

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