嗜酸性粒细胞颗粒关键碱性蛋白抗体

英文名称    p53 apoptosis effector related to PMP22    

中文名称    p53凋亡相关作用蛋白PMP22抗体    

别    名    KCP 1; KCP-1; KCP1; Keratinocyte associated protein 1; Keratinocyte-associated protein 1; Keratinocytes associated protein 1; KRTCAP 1; KRTCAP1; p53 apoptosis effector related to PMP 22; p53 apoptosis effector related to PMP-22; p53 apoptosis effector related to PMP22; P53 induced protein PIGPC1; P53-induced protein PIGPC1; Perp; PERP TP53 apoptosis effector; PERP_HUMAN; PIGPC 1; PIGPC1; THW antibody TP53 apoptosis effector; Transmembrane protein THW.    

p53凋亡相关作用蛋白PMP22抗体        

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  细胞凋亡  细胞骨架      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    21kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human p53 apoptosis effector related to PMP22    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

p53凋亡相关作用蛋白PMP22抗体产品介绍    Function:
Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway.

Subcellular Location:
Cell junction, desmosome. Cell membrane; Multi-pass membrane protein. Note=Associated with desmosomes.

Tissue Specificity:
Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts.

Similarity:
Belongs to the TMEM47 family.

Gene ID:
64065

Database links:

Entrez Gene: 64065 Human

Entrez Gene: 64058 Mouse

Omim: 609301 Human

SwissProt: Q96FX8 Human

SwissProt: Q9JK95 Mouse

Unigene: 201446 Human

Unigene: 28209 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

p53凋亡相关作用蛋白PMP22抗体

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hz-3075R phospho CSF1R (Tyr699)  磷酸化巨噬细胞集落刺激因子受体抗体

hz-3076R phospho-M-CSF Receptor(Tyr708)  磷酸化巨噬细胞集落刺激因子受体抗体

hz-3077R phospho-CSF1R (Tyr723)  磷酸化巨噬细胞集落刺激因子受体抗体

hz-3078R phospho-M-CSF Receptor(Tyr809)  磷酸化巨噬细胞集落刺激因子受体抗体

hz-3079R phospho-CSF1R(Tyr923)  磷酸化巨噬细胞集落刺激因子受体抗体

hz-1569R MCT1  单羧酸转运蛋白-1抗体

hz-1981R MCM2  微小染色体维持缺陷蛋白2抗体

hz-1982R MCM3  微小染色体维持缺陷蛋白3抗体

hz-2721R MCM5  微小染色体维持缺陷蛋白5抗体

hz-1983R MCM7  微小染色体维持缺陷蛋白7抗体

hz-1352R Mcl1/BCL2L3  髓样分化蛋白2抗体

hz-3265R Phospho-Mcl1 (Ser159/Thr163)  磷酸化髓样细胞白血病-1抗体

hz-3996R MDH1  可溶性苹果酸脱氢酶抗体

hz-1043R MDM2  双微体2癌基因抗体

hz-3266R Phospho-MDM2 (Ser166)  磷酸化双微体2癌基因抗体

hz-5470R Phospho-MDM2(Thr218)  磷酸化双微体2癌基因抗体

hz-5471R Phospho-MDM2(Ser186)  磷酸化双微体2癌基因抗体

hz-1468R MDR1/p-GP/CD243 (C-terminus)  多药耐药蛋白/P-糖蛋白抗体(C端)

hz-0563R MDR1/p-GP/CD243 (N-terminus)  多药耐药蛋白/P-糖蛋白抗体

hz-5915R MBD1/PCM1  甲基化CpG结合蛋白抗体

hz-3823R MeCP2  甲基化CpG结合蛋白2抗体

hz-1400R MEF2A  肌细胞增强因子2抗体

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