衰老标记蛋白30抗体

英文名称    Regucalcin    

中文名称    衰老标记蛋白30抗体    

别    名    Gluconolactonase; GNL; RC; Regucalcin; RGN; RGN_HUMAN; Senescence marker protein 30; SMP 30; SMP-30.    

衰老标记蛋白30抗体       

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  信号转导  结合蛋白      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    33kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human Regucalcin    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

衰老标记蛋白30抗体 产品介绍    background:
Regucalcin is a Ca2+ binding protein that is encoded by a highly conserved gene in vertebrate species. Regucalcin is greatly expressed in liver and kidney cortex, and the expression is mediated through a Ca2+ signaling mechanism with AP1 and NFI-A1 as transcriptional factors. It plays a multifunctional role as a regulatory protein in intracellular signaling processes in the cytoplasm and nucleus of cells including the maintenance of intracellular Ca2+ homeostasis, the regulation of various Ca2+ dependent protein kinases and tyrosine kinases, protein phosphatases, nitric oxide (NO) synthase, and the suppression of nuclear DNA and RNA syntheses. Regucalcin has suppressive effects on cell proliferation, cell death and apoptosis, and is suggested to play a physiologic role in the maintenance of cellular homeostasis.

Function:
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities.

Subunit:
Monomer. 

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the SMP-30/CGR1 family. 

Gene ID:
9104

Database links:

Entrez Gene: 9104 Human

Omim: 300212 Human

SwissProt: Q15493 Human

SwissProt: Q5JRR5 Human

Unigene: 77854 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

衰老标记蛋白30抗体 

hz-0738R Livin  凋亡抑制蛋白抗体

hz-3948R LKB1  苏氨酸蛋白激酶LKB1抗体

hz-1532R phospho-LKB1 (Thr363)  磷酸化丝氨酸/苏氨酸蛋白激酶抗体

hz-3248R phospho-LKB1(Ser334)  磷酸化丝氨酸/苏氨酸蛋白激酶抗体

hz-3249R phospho-LKB1(Ser428)  磷酸化丝氨酸/苏氨酸蛋白激酶抗体

hz-3250R Phospho-LKB1(Thr189)  磷酸化丝氨酸/苏氨酸蛋白激酶抗体

hz-0824R LFABP/FABP-1  肝脏型脂肪酸结合蛋白抗体

hz-0897R LFABP/FABP-2  肝脏型脂肪酸结合蛋白抗体

hz-0821R laminin  层粘连蛋白抗体

hz-1526R Laminin Beta 1  层粘连蛋白β1抗体

hz-5122R Laminin B2 gamma 1  层粘连蛋白B2γ1抗体

hz-1839R lamin A/C  核纤层蛋白A抗体

hz-3254R Phospho-Lamin A/C(Ser22)  磷酸化核纤层蛋白A/C抗体

hz-1840R Lamin B [Nuclear Envelope Marker]  核纤层蛋白B抗体(细胞核内参)

hz-5081R Lamin B Receptor  核纤层蛋白B受体抗体

hz-1841R lamin A/C  核纤层蛋白A/C抗体

hz-2044R LOX-1/OLR1  凝集素样氧化型低密度脂蛋白受体抗体

hz-2880R EDG2/LPA1  溶血磷脂酸受体蛋白1抗体

hz-2881R EDG4/LPA2  溶血磷脂酸受体蛋白2抗体

hz-2882R EDG7/LPA3  溶血磷脂酸受体蛋白3抗体

hz-2883R EDG6/SLP4  内皮细胞的分化蛋白6抗体

hz-0759R Lpin1 protein  Lpin1 抗体

hz-0760R Lpin1 protein  Lpin1 抗体

hz-1973R LPL/PLASTIN2  脂蛋白脂酶抗体

hz-2336R LPL protein  内皮脂肪酶

hz-2397R Endothelial lipase  内皮脂肪酶抗体

hz-0976R LPLUNC1  鼻咽癌癌基因抗体

hz-1844R LRIG1  LRIG1抗体

hz-3861R LPP/LIM protein  脂肪瘤相关蛋白抗体

hz-1845R LRIG2  LRIG2抗体

hz-1846R LRIG3  LRIG3抗体

hz-0661R LRP/MVP  肺耐药相关蛋白抗体

hz-2677R LRP1/CD91  低密度脂蛋白受体相关蛋白1抗体

hz-5409R phospho-LRP1(Ser4523)  磷酸化低密度脂蛋白受体相关蛋白1抗体

hz-3909R Lrp2/Megalin  糖蛋白gp330抗体