mRNA结合蛋白抗体

英文名称    RAE1    

中文名称    mRNA结合蛋白抗体    

别    名    RAE-1; MIG 14; MIG14; Mnrp 41; Mnrp41; mRNA associated protein mrnp 41; mRNA binding protein 41 kD; mRNA export protein; MRNP 41; MRNP41; RAE 1; RAE1 (RNA export 1 S.pombe) homolog; RAE1 homolog; Rae1 protein homolog; RAE1 RNA export 1 homolog; RNA export 1; RNA export 1 homolog; Homolog of yeast Rae1 mRNA associated protein of 41 kDa. RAE1L_HUMAN    

mRNA结合蛋白抗体     

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  免疫学  信号转导  转录调节因子  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    41kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RAE1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

mRNA结合蛋白抗体 产品介绍    background: ubMed    PubMed    

产品介绍    background:
Mutations in Rae1 and Gle2(Saccharomyces cerevisae homolog) genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Depletion of Rae1 from extracts or cells severely inhibits mitotic spindle assembly. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Function:
Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.

Subunit:
Interacts with NUP98.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the WD repeat rae1 family.
Contains 7 WD repeats. 

Gene ID:
8480

Database links:

Entrez Gene: 8480 Human

Omim: 603343 Human

SwissProt: P78406 Human

SwissProt: Q3SYL7 Human

Unigene: 371698 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

mRNA结合蛋白抗体 

hz-1051R Integrin beta 7  整合素β7抗体

hz-2016R Integrin Alpha V + Beta1  整合素αVβ1抗体

hz-1310R Integrin Alpha V + Beta 3 (CD51+CD61)  整合素αVβ3抗体

hz-1356R Integrin Alpha V + Beta 5  整合素αVβ5抗体

hz-5791R Integrin Alpha V + Beta 6  整合素αVβ6抗体

hz-1274R Integrin alpha E/CD103  整合素αE抗体

hz-1109R IQGAP1  支架蛋白抗体

hz-1404R IRF-1/MAR1  干扰素调节因子1抗体

hz-1427R IRAK2  白介素-1受体相关激酶2抗体

hz-3192R Phospho-IRAK1 (Ser376)  磷酸化白介素-1受体相关激酶1抗体

hz-3193R Phospho-IRAK1 (Thr209)  磷酸化白介素-1受体相关激酶1抗体

hz-3194R Phospho-IRAK1 (Thr387)  磷酸化白介素-1受体相关激酶1抗体

hz-2993R IRF3  干扰素调节因子3

hz-3195R Phospho-IRF3 (Ser396)  磷酸化干扰素调节因子3

hz-2440R IRAK4  白介素-1受体相关激酶4抗体

hz-4080R phospho-IRAK4(Thr345)  磷酸化白介素-1受体相关激酶4抗体

hz-2216R IL-1RA  白介素-1受体拮抗剂抗体

hz-2594R IL-1R1/CD121a/IL1 Receptor I  白介素1受体1抗体

hz-5394R phospho-IL-1R1(Tyr496)  磷酸化白介素1受体1抗体

hz-2595R IL-1R2 /CD121b/IL1 Receptor II  白介素1受体2抗体

hz-2382R ST2  白细胞介素1受体相关蛋白抗体

hz-2500R IRF4  干扰素调节因子4抗体

hz-4015R IRGM  免疫相关鸟苷三磷酸酶基因抗体

hz-2634R ILT2/CD85j  细胞表面免疫球蛋白样转录因子2抗体

hz-2994R IRF7  干扰素调节因子7抗体

hz-3196R Phospho-IRF7 (Ser471/472)  磷酸化干扰素调节因子7抗体

hz-0242R IRS P53  胰岛素受体底物p53蛋白抗体

hz-0172R IRS1  胰岛素受体底物-1抗体

hz-2736R phospho-IRS-1(Ser307)  磷酸化胰岛素受体底物p-IRS-1/2抗体

hz-3197R phospho-IRS1(Ser1101)  磷酸化胰岛素受体底物-1抗体

hz-3198R phospho-IRS1(Ser302)  磷酸化胰岛素受体底物-1抗体

hz-3199R phospho-IRS1(Ser332/336)  磷酸化胰岛素受体底物-1抗体

hz-3200R phospho-IRS1(Ser612)  磷酸化胰岛素受体底物-1抗体

hz-3201R phospho-IRS1(Ser636/639)  磷酸化胰岛素受体底物-1抗体

hz-3202R phospho-IRS1(Ser789)  磷酸化胰岛素受体底物-1抗体

hz-3203R phospho-IRS1(Tyr1222)  磷酸化胰岛素受体底物-1抗体

hz-3204R phospho-IRS1(Tyr895)  磷酸化胰岛素受体底物-1抗体

hz-5396R phospho-IRS1(Ser312)  磷酸化胰岛素受体底物-1抗体

hz-5446R phospho-IRS1(Thr176)  磷酸化胰岛素受体底物1抗体

hz-0173R IRS-2  胰岛素受体底物-2抗体

hz-5397R phospho-IRS-2(Ser731)  磷酸化胰岛素受体底物2抗体

hz-0186R IRS-3  胰岛素受体底物-3抗体

hz-0187R IRS-4  胰岛素受体底物-4抗体

hz-0641R Integrin alpha 4/CD49d  整合素α4抗体

hz-2055R Integrin alpha 4+Beta 7  整合素α4β7抗体