视黄酸受体应答蛋白1抗体

英文名称    RARRES1    

中文名称    视黄酸受体应答蛋白1抗体    

别    名    Retinoic acid receptor responder protein 1; RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein; TIG1_HUMAN.    

视黄酸受体应答蛋白1抗体        

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    33kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RARRES1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

视黄酸受体应答蛋白1抗体产品介绍    background:
RARRES1 (Retinoic acid receptor responder 1) is a retinoid-regulated gene whose expression is down-regulated through DNA hypermethylation. It was originally identified as a target gene that was induced by the synthetic retinoid tazarotene (AGN 190168). Its expression is upregulated by retinoic acid receptor-specific, but not by retinoid X receptor-specific retinoids. Although the function of RARRES1 is not entirely clear, it is thought to act as a tumor suppressor of a variety of human cancers since inactivation of RARRES1 is involved in the malignant progression of prostate cancer. It may also function as a cell adhesion molecule. Additionally, RARRES1 may also have protease inhibitor activity and inhibit the degradation of extracellular matrix.

Subcellular Location:
Membrane; Single-pass type II membrane protein (Potential).

Similarity:
Belongs to the protease inhibitor I47 (latexin) family.

Gene ID:
5918

Database links:

Entrez Gene: 5918 Human

Omim: 605090 Human

SwissProt: P49788 Human

Unigene: 131269 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

视黄酸受体应答蛋白1抗体

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