英文名称 RELM alpha
中文名称 抵抗素样分子α抗体
别 名 RELMa; RELM alpha; Cysteine rich secreted protein FIZZ1; Cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; FIZZ1; FIZZ1; Parasite induced macrophage novel gene 1 protein; Parasite-induced macrophage novel gene 1 protein; Pmng1; RELMa; RELMalpha; Resistin like alpha; Resistin Like Protein Alpha; Resistin Like Protein Alpha; Resistin-like alpha; RETNA_MOUSE; Retnla.
抵抗素样分子α抗体
说 明 书 0.1ml 0.2ml
研究领域 信号转导 生长因子和激素
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Mouse, Rat,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 9kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse RELMa
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
抵抗素样分子α抗体 产品介绍 background:
A family of resistin-like molecules (RELMs) has been identified in rodents and humans. RELM alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family; Resistin, RELM alpha and RELM beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain. RELM alpha and Resistin are secreted exclusively by adipocytes while RELM beta is expressed in the epithelium of the colon and small bowel. The RELMs together with resistin comprise a class of tissue-specific signaling molecules. The physiological role and molecular targets of RELM alpha are still unknown.
Function:
Probable hormone. Plays a role in pulmonary vascular remodeling.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Tissue Specificity:
Highest levels in adipose tissue.
Similarity:
Belongs to the resistin/FIZZ family.
Gene ID:
57262
Database links:
Entrez Gene: 57262 Mouse
SwissProt: Q9EP95 Mouse
Unigene: 441868 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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