RAP1GAP酶激活蛋白抗体

英文名称    RAP1GAP    

中文名称    RAP1GAP酶激活蛋白抗体    

别    名    Rap1 GTPase activating protein 1; RAP1 GTPase activating protein; RAP1GA1; Rap1ga1 protein; RAP1GAP1; RAP1GAPII; RAPGAP; KIAA0474; RPGP1_HUMAN.    

RAP1GAP酶激活蛋白抗体      

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  免疫学  信号转导  激酶和磷酸酶      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    73kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RAP1GAP.    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RAP1GAP酶激活蛋白抗体  产品介绍    background:
RAP1GAP, an 85/95kDa protein, is a member of a family of GAPs specific for Rap1. Though to be an important tumor suppressor, Rap1GAP has no sequence homology with other GAPs such as RasGAP, RanGAP and RhoGAP. Purified as a cytosolic and membrane-bound protein, both isoforms consist of two monomers each contain a dimerization and a catalytic domain. Mutations in the GAP domain of the tumor suppressor tuberin, can cause benign tumor phenotype tuberous sclerosis. There are 2 isoforms produced by alternative splicing.

Function:
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.

Subunit:
Homodimer and heterodimer with RAP1B.

Subcellular Location:
Golgi apparatus membrane; Peripheral membrane protein.

Tissue Specificity:
Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.

Similarity:
Contains 1 GoLoco domain.
Contains 1 Rap-GAP domain.

Database links:
UniProtKB/Swiss-Prot: P47736.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.     

RAP1GAP酶激活蛋白抗体  

hz-1464R GnRHR  促性腺激素释放激素受体抗体

hz-1469R GRP75  G蛋白偶联受体75抗体

hz-2575R GPA/GYPA/CD235a  血型糖蛋白A/涎糖蛋白抗体

hz-1807R GPR78  G蛋白偶联受体78抗体

hz-2501R KiSS1R/GPR54  G蛋白偶联受体54抗体

hz-2582R GPR109A/HM74A  G蛋白偶联受体109A抗体

hz-3939R G protein alpha S  G蛋白αS抗体（鸟嘌呤核苷酸结合蛋白Gα s）

hz-3882R GPX1  谷胱甘肽过氧化酶1

hz-1082R GRK1  G蛋白偶合受体激酶1抗体

hz-3883R GPX3  谷胱甘肽过氧化酶3

hz-3884R GPX4  谷胱甘肽过氧化酶4抗体

hz-1209R GRK2/BARK1/ADRBK1  G蛋白偶合受体激酶2抗体

hz-3594R GRIM19  干扰素/维甲酸诱导凋亡相关基因抗体

hz-1803R GRM1  促代谢型谷氨酸受体1抗体

hz-1161R GRM2/GLUR2  促代谢型谷氨酸受体2抗体

hz-3169R Phospho-GRM2/GLUR2 (Tyr869/873/876)  磷酸化促代谢型谷氨酸受体2抗体

hz-3170R Phospho-GRM2/GLUR2(Tyr876)  磷酸化促代谢型谷氨酸受体2抗体

hz-1237R GRM3  促代谢型谷氨酸受体M3抗体

hz-1894R GRM4/mGluR4  促代谢型谷氨酸受体4抗体

hz-1247R GRM5/mGluR5  促代谢型谷氨酸受体5抗体

hz-2139R GRM2+GRM4  促代谢型谷氨酸受体2+4抗体

hz-0863R GRO Alpha/GRO-1/CXCL1  生长调节致癌基因-1抗体GROa GROβ

hz-1162R MIP2/GRO Beta/CXCL2  巨噬细胞炎症蛋白2（ GRＯβ）抗体

hz-2547R GRO gamma/CXCL3  生长调节致癌基因gamma（GRＯγ）抗体

hz-2548R CXCL4/PF4  血小板因子4抗体

hz-2549R CXCL5  上皮中性粒细胞活化肽78抗体

hz-0011R GRP  促胃泌素释放肽抗体

hz-1219R GRP78/BIP/HSPA5  葡萄糖调节蛋白78抗体（热休克蛋白70蛋白5）

hz-0194R GRP94/HSP gp96  葡萄糖调节蛋白94抗体

hz-4692R phospho-GSK3 Alpha(Ser21)  磷酸化葡萄糖合成激酶-3α抗体

hz-2091R GSK3 alpha  葡萄糖合成激酶3α抗体

hz-3161R Phospho-GSK3 alpha(Ser21)  磷酸化葡萄糖合成激酶3α抗体 GSK3α(Phospho-Ser21)

hz-2359R Glycogen synthase 1  葡萄糖合成酶1抗体

hz-3190R Phospho-Glycogen synthase 1(Ser641)  磷酸化葡萄糖合成酶1抗体

hz-3989R Glycogen synthase 2  葡萄糖合成酶2抗体

hz-0028M GSK-3 Beta (CT)  葡萄糖合成激酶-3β抗体

hz-0028R GSK-3 Beta (CT)  葡萄糖合成激酶-3β抗体