Ras相关区域家族蛋白4抗体

英文名称    RASSF4    

中文名称    Ras相关区域家族蛋白4抗体    

别    名    AD037; Ras association (RalGDS/AF 6) domain family 4; Ras association domain family 4; Ras association (RalGDS/AF 6) domain family member 4; Ras association domain containing protein 4; RASSF 4; Tumor suppressor RASSF4; RASF4_HUMAN.    

Ras相关区域家族蛋白4抗体         

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  免疫学  信号转导  细胞周期蛋白  G蛋白偶联受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    37kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RASSF4    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

Ras相关区域家族蛋白4抗体 产品介绍    background:
The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described.

Function:
Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.

Subunit:
Interacts directly with activated KRAS in a GTP-dependent manner.

Tissue Specificity:
Widely expressed. Frequently down-regulated in tumor cell lines.

Similarity:
Contains 1 Ras-associating domain. 
Contains 1 SARAH domain. 

Database links:
UniProtKB/Swiss-Prot: Q9H2L5.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

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