英文名称 phospho-Rab24(Ser95)
中文名称 磷酸化ras基因相关蛋白Rab24抗体
别 名 RAB24(phospho S95); Rab 24; Rab-24; Ras-related protein Rab-24; RAB24_HUMAN.
磷酸化ras基因相关蛋白Rab24抗体
说 明 书 0.1ml
产品类型 磷酸化抗体
研究领域 肿瘤 免疫学 细胞凋亡 转录调节因子
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human Rab2 around the phosphorylation site of Ser95
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
磷酸化ras基因相关蛋白Rab24抗体产品介绍 background:
A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.
Function:
May be involved in autophagy-related processes (By similarity).
Subunit:
Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB. Interacts with ZFYVE20.
Subcellular Location:
Cytoplasm, cytosol. Membrane; Lipid-anchor (By similarity). Note=Only about 20-25% is recovered in the particulate fraction.
Post-translational modifications:
Isoprenylation is inefficient compared to other Rab family members.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
Database links:
UniProtKB/Swiss-Prot: Q969Q5.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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