磷酸化ras基因相关蛋白Rab24抗体

英文名称    phospho-Rab24(Ser95)    

中文名称    磷酸化ras基因相关蛋白Rab24抗体    

别    名    RAB24(phospho S95); Rab 24; Rab-24; Ras-related protein Rab-24; RAB24_HUMAN.    

磷酸化ras基因相关蛋白Rab24抗体        

说 明 书    0.1ml      

产品类型    磷酸化抗体     

研究领域    肿瘤  免疫学  细胞凋亡  转录调节因子      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    23kDa    

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated Synthesised phosphopeptide derived from human Rab2 around the phosphorylation site of Ser95    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

磷酸化ras基因相关蛋白Rab24抗体产品介绍    background:
A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. The GTPase Rab24 is thought to be involved in the regulation of vesicular transport associated with autophagy.

Function:
May be involved in autophagy-related processes (By similarity).

Subunit:
Unlike other Rab family members, does not interact with GDP dissociation inhibitors (GDIs), including ARHGDIA and ARHGDIB. Interacts with ZFYVE20.

Subcellular Location:
Cytoplasm, cytosol. Membrane; Lipid-anchor (By similarity). Note=Only about 20-25% is recovered in the particulate fraction.

Post-translational modifications:
Isoprenylation is inefficient compared to other Rab family members.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

Database links:
UniProtKB/Swiss-Prot: Q969Q5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

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