Ras-GTP酶激活蛋白3抗体

英文名称    RASA3    

中文名称    Ras-GTP酶激活蛋白3抗体    

别    名    GAP III; GAP1(IP4BP); GAP1IP4BP; GAPIII; GTPase activating protein III; Inositol 1 3 4 5 tetrakisphosphate binding protein; Inositol 1345 tetrakisphosphate binding protein; Ins P4 binding protein; Ins(1 3 4 5)P4 binding protein; Ins(1345)P4 binding protein; Ras GTPase activating protein 3; RAS p21 protein activator 3; RASA 3.RASA3_HUMAN    

 Ras-GTP酶激活蛋白3抗体

说 明 书    0.2ml      

研究领域    免疫学  信号转导  G蛋白偶联受体      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    91kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RASA3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

 Ras-GTP酶激活蛋白3抗体产品介绍    background:
RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4).

Function:
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.

Subcellular Location:
Cell membrane.

Similarity:
Contains 1 Btk-type zinc finger.
Contains 2 C2 domains.
Contains 1 PH domain.
Contains 1 Ras-GAP domain. 

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

 Ras-GTP酶激活蛋白3抗体

hz-1997R NCX2/SLC8A2  钠钙交换蛋白2抗体

hz-3956R NDUFA1  NADH氧化还原酶辅酶1抗体

hz-3957R NDUFA10  NADH氧化还原酶辅酶10抗体

hz-3958R NDUFA8  NADH脱氢酶α家族8抗体

hz-3888R NDUFS3  线粒体复合物NDUFS3蛋白抗体

hz-2401R Nebulin  伴肌动蛋白抗体

hz-3961R NDUFS4  线粒体复合物NDUFS4蛋白抗体

hz-3959R NDUFV1  NADH脱氢酶黄素蛋白1抗体

hz-3960R NDUFV2  NADH脱氢酶黄素蛋白2抗体

hz-2057R NCX3  钠钙交换蛋白3抗体

hz-3886R NCF1  嗜中性粒细胞胞浆因子1抗体

hz-1676R MG  鸡毒支原体抗体

hz-3616R NCF/NCF4/p40phox  嗜中性粒细胞胞浆因子4抗体

hz-3497R Phospho-p40phox (Thr154)  磷酸化嗜中性粒细胞胞浆因子4抗体

hz-3550R MYOG/Myogenin  肌红蛋白抗体(肌细胞生成素)

hz-0513R Nephrin  肾小球细胞粘附分子受体抗体

hz-2679R Nectin 2/CD112  细胞粘附分子CD112抗体

hz-4051R Nectin 4  脊髓灰质炎病毒受体相关蛋白4抗体

hz-2344R NLK/Nhzo-like kinase  Nhzo样激酶抗体

hz-6181R Nectin 3/CD113  细胞粘附分子3抗体（脊髓灰质炎病毒受体相关蛋白3）

hz-0006R Nestin  巢蛋白/神经上皮干细胞蛋白抗体

hz-0008R Nestin  巢蛋白/神经上皮干细胞蛋白抗体

hz-0268R Neurobeachin  蛋白激酶锚定蛋白抗体

hz-1473R AKAP95/AKAP8  蛋白激酶A锚定蛋白95抗体

hz-1613R NeuN  神经元核抗原抗体

hz-2464R Nrn1/Cpg15/Neuritin  转化神经突起蛋白抗体

hz-1055R Neurocan  神经粘蛋白抗体

hz-1859R NGB/neuroglobin  脑红蛋白/神经血红蛋白/神经球蛋白抗体

hz-1517R NeuroD1/NEUROD  神经细胞分化因子1抗体

hz-0289R Neurofascin/Nfasc155  神经束蛋白155抗体

hz-3692R Neurogenin 2/NGN2  神经元素2抗体

hz-0072R NT/NTS1/NTRH  神经降压素抗体

hz-1366R NF2/Neurofibromin 2  2型神经纤维瘤抗体

hz-3291R Phospho-NF2(Ser518)  磷酸化2型神经纤维瘤抗体

hz-4140R NF1/Neurofibromin 1  1型神经纤维瘤抗体

hz-1417R NFATc1/NFAT2  活化T细胞核因子1蛋白抗体

hz-5520R phospho-NF1(Ser2515)  磷酸化1型神经纤维瘤抗体

hz-2680R NFAM1/CNAIP  NFAM1抗体

hz-5521R phospho-NF1(Ser2817)  磷酸化1型神经纤维瘤抗体