RNA结合基因蛋白3抗体

英文名称    RBM3    

中文名称    RNA结合基因蛋白3抗体    

别    名    Putative RNA binding protein 3; RNA binding motif (RNP1, RRM) protein 3; RNA binding motif protein 3; RNPL; RP23-27I6.7; RBM3_HUMAN.    

RNA结合基因蛋白3抗体       

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  免疫学  染色质和核信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    17kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RBM3    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

RNA结合基因蛋白3抗体产品介绍    background:
This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008].

Function:
Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphoryaltion of translation initiation factors and active polysome formation (By similarity).

Subunit:
Interacts with RPL4. Associates with the 60S ribosomal subunits in an RNA-independent manner. Associates with ribosomes.

Subcellular Location:
Nucleus. Cytoplasm. Cell projection, dendrite.

Post-translational modifications:
Arg-105 is dimethylated, probably to asymmetric dimethylarginine. 
Phosphorylated (By similarity). 

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

Database links:
UniProtKB/Swiss-Prot: P98179.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

RNA结合基因蛋白3抗体

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hz-4605R MMP-2  基质金属蛋白酶-2抗体

hz-4597R MMP-1  基质金属蛋白酶-1抗体

hz-0575R MMP-13  基质金属蛋白酶13抗体

hz-0414R MMP-14  基质金属蛋白酶-14抗体

hz-1855R MMP-15  基质金属蛋白酶-15抗体

hz-1856R MMP-16  基质金属蛋白酶-16抗体

hz-0985R MMP-20  基质金属蛋白酶20抗体

hz-1862R MMP-17  基质金属蛋白酶-17抗体

hz-5787R MMP19  基质金属蛋白酶18/19

hz-5788R MMP20  基质金属蛋白酶20

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hz-5874R MMP-22  基质金属蛋白酶22抗体

hz-5875R MMP-23  基质金属蛋白酶23抗体

hz-1377R MMP-26  基质金属蛋白酶-26抗体

hz-5876R MMP-28  基质金属蛋白酶28抗体

hz-1344R MMP-10  基质金属蛋白酶-10抗体

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