肿瘤相关表面抗原EBAG9抗体

英文名称    RCAS1    

中文名称    肿瘤相关表面抗原EBAG9抗体    

别    名    BAG9; Cancer associated surface antigen; Cancer associated surface antigen RCAS1; EB9; EBAG 9; Estrogen receptor binding fragment associated gene 9 protein; Estrogen receptor binding site associated antigen 9; PDAF; RCAS 1; RCAS1; Receptor binding cancer antigen expressed on SiSo cells.    

 肿瘤相关表面抗原EBAG9抗体

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  信号转导  生长因子和激素  细胞类型标志物  肿瘤细胞生物标志物      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    24kDa    

细胞定位    细胞浆 细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human EBAG9/RCAS1    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

 肿瘤相关表面抗原EBAG9抗体产品介绍    background:
EBAG9 is a type III transmembrane protein that is predominantly located in the Golgi. It induces apoptosis of natural killer (NK)/T cells and plays a role in immune invasion, possibly in relation to Epstein-Bar virus infection. EBAG9 is abundantly expressed in prostate cancer cells when compared to normal epithelial cells, and immunodetection of EBAG9 expression can be a negative prognostic indicator for patients with prostate cancer.

Function:
May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

Subunit:
Homodimer. 

Subcellular Location:
Golgi apparatus membrane; Single-pass type III membrane protein. Note=According to PubMed:10426319, it also exists as a soluble form which has the same biological activities. The existence of such soluble form is however uncertain. 

Tissue Specificity:
Widely expressed. Expressed in ovary, testis, prostate, thymus, muscle and heart, but not in small intestine, colon, lymph nodes, or peripherical blood lymphocytes. The protein is not detected in any of the above organs. 

Database links:

Entrez Gene: 9166 Human

Entrez Gene: 55960 Mouse

Entrez Gene: 299864 Rat

Omim: 605772 Human

SwissProt: O00559 Human

SwissProt: Q9D0V7 Mouse

SwissProt: Q5PQP2 Rat

Unigene: 409368 Human

Unigene: 489725 Mouse

Unigene: 64132 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

 肿瘤相关表面抗原EBAG9抗体

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hz-1763R EphA1/Ephrina1/Ephrin A1 Receptor  内皮细胞受体蛋白酪氨酸激酶A抗体（肿瘤坏死因子α诱导蛋白4）

hz-1764R EphA4  酪氨酸蛋白激酶A4抗体

hz-2764R Ephrin B  Ephrin B抗体

hz-3217R phospho-Ephrin B(Tyr329)  磷酸化Ephrin B抗体

hz-3167R phospho-Ephrin B(Tyr316)  磷酸化Ephrin B抗体

hz-3128R phospho-Ephrin B(Ser300)  磷酸化Ephrin B抗体

hz-3129R phospho-Ephrin B(Tyr324/329)  磷酸化Ephrin B抗体

hz-6047R Ephrin A3/EFNA3  酪氨酸蛋白激酶A3受体抗体

hz-6048R Ephrin A5  酪氨酸蛋白激酶A5受体抗体

hz-5887R HPSE2  乙酰肝素酶样蛋白抗体

hz-0485R EphA2/Eph receptor A2  内皮细胞受体蛋白酪氨酸激酶抗体

hz-3126R Phospho-EphA2(Tyr594)  磷酸化酪氨酸蛋白激酶A2受体抗体

hz-1455R EphA4 R/Eph receptor A4  酪氨酸蛋白激酶A4受体抗体

hz-0247R EphB2 R  酪氨酸蛋白激酶受体B2抗体

hz-2343R EPO  红细胞生成素抗体

hz-1424R EPOR  红细胞生成素受体抗体

hz-3880R EPHX2  胞浆环氧化物水解酶抗体

hz-2365R Eppin  附睾蛋白酶抑制蛋白

hz-3881R EPX  嗜酸性粒细胞过氧化物酶抗体

hz-2571R EphB6  酪氨酸蛋白激酶受体B6抗体

hz-3848R EPS8  表皮生长因子受体底物8抗体

hz-0725R ERα/ESR1  雌激素受体α抗体

hz-0021M ERAB/HSD17B10  内质网Aβ相关结合蛋白抗体

hz-5890R Lumican  基膜聚糖蛋白抗体

hz-1726R ERCC1  DNA切除修复蛋白1抗体

hz-0022R ERK2/MAPK1  丝裂原活化蛋白激酶1抗体

hz-1736R phospho-MEK1/MAPKK1(Ser298)  磷酸化丝裂原活化蛋白激酶激酶1抗体

hz-3269R phospho-MEK1(Thr286)  磷酸化丝裂原活化蛋白激酶激酶1抗体

hz-3270R Phospho-MEK1/2(Ser218/222)  磷酸化丝裂原活化蛋白激酶激酶1/2抗体

hz-3722R Phospho-MEK1/2(Ser222)  磷酸化丝裂原活化蛋白激酶激酶1/2抗体

hz-1522R phospho-ERK1/MAPK-1/2(Thr183/185)  磷酸化丝裂原活化蛋白激酶1/2抗体

hz-5411R phospho-MEK1/MAP2K1(Ser385)   磷酸化丝裂原活化蛋白激酶1抗体

hz-5412R phospho-MEK1/MAP2K1(Thr292)  磷酸化丝裂原活化蛋白激酶1抗体

hz-1645R phospho-ERK1(Thr202/Tyr204)  磷酸化丝裂原活化蛋白激酶1抗体

hz-5413R phospho-MEK1/MAP2K1(Thr386)  磷酸化丝裂原活化蛋白激酶1抗体

hz-5414R phospho-MEK1+MEK2(Ser222/Ser226)  磷酸化丝裂原活化蛋白激酶1抗体

hz-2637R ERK1/2(p44/42 MAPK)  丝裂原活化蛋白激酶1/2抗体

hz-3016R phospho-ERK1/2(Thr202/Tyr204)( p44/42 MAPK)   磷酸化丝裂原活化蛋白激酶1/2抗体

hz-1646R phospho-ERK1(Thr202/Tyr204)+ERK2(Thr183/Tyr185)  磷酸化丝裂原活化蛋白激酶1/2抗体

hz-3292R phospho-ERK1(Thr197/Thr202)  磷酸化丝裂原活化蛋白激酶1/2抗体

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hz-0996R EphB2/Eph receptor B2  酪氨酸蛋白激酶受体B2抗体

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