肿瘤血管内皮标记蛋白2抗体

英文名称    RASD2    

中文名称    肿瘤血管内皮标记蛋白2抗体    

别    名    GTP binding protein Rhes; GTP-binding protein Rhes; Ras homolog enriched in striatum; RASD 2; RASD family member 2; RASD2; Rhes; RHES_HUMAN; TEM 2; TEM2; Tumor endothelial marker 2.    

肿瘤血管内皮标记蛋白2抗体       

说 明 书    0.1ml  0.2ml      

研究领域    肿瘤  信号转导  生长因子和激素  细胞类型标志物  肿瘤细胞生物标志物  G蛋白信号      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Horse, Rabbit,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    30kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RASD2/Tumor endothelial marker 2    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

肿瘤血管内皮标记蛋白2抗体 产品介绍    background:
GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.

Function:
GTPase signaling protein that binds to and hydrolyzes GTP. Regulates signaling pathways involving G-proteins-coupled receptor and heterotrimeric proteins such as GNB1, GNB2 and GNB3. May be involved in selected striatal competencies, mainly locomotor activity and motor coordination.

Subunit:
Monomer (Potential). Interacts with PIK3CA and UBE2I. Interacts with GNB1, GNB2 and GNB3. Interacts with HTT; interacts with mutant HTT (mHTT) with a much higher affinity than wild type HTT.

Subcellular Location:
Cell membrane; Lipid-anchor.

Tissue Specificity:
Pancreatic endocrine cells (islets of Langerhans).

Post-translational modifications:
Farnesylated. Farnesylation is required for membrane targeting.

Similarity:
Belongs to the small GTPase superfamily. RasD family.

Database links:
UniProtKB/Swiss-Prot: Q96D21.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

肿瘤血管内皮标记蛋白2抗体 

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