英文名称 RNF19B
中文名称 环指蛋白19B抗体
别 名 E3 ubiquitin-protein ligase RNF19B; IBR domain containing 3; IBR domain-containing protein 3; IBRDC3; Natural killer lytic-associated molecule; NKLAM; RING finger protein 19B; RN19B_HUMAN; rnf19b.
环指蛋白19B抗体
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学 t-淋巴细胞
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 78kDa
细胞定位 细胞浆 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF19B
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
环指蛋白19B抗体 产品介绍 background:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.
Function:
E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells.
Subunit:
Interacts with UBE2L3, UBE2L6 and UCKL1.
Subcellular Location:
Cytoplasmic granule membrane.
Tissue Specificity:
Expressed specifically in natural killer cells, activated macrophages and cytotoxic T-cells. Present in natural killer cells
Similarity:
Belongs to the RBR family. RNF19 subfamily.
Contains 1 IBR-type zinc finger.
Contains 2 RING-type zinc fingers.
Gene ID:
127544
Database links:
Entrez Gene: 127544 Human
Omim: 610872 Human
SwissProt: Q6ZMZ0 Human
Unigene: 591504 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环指蛋白19B抗体
hz-8167R CHCHD6 卷曲螺旋结构域蛋白CHCHD6抗体
hz-8168R GTF2B 通用转录因子GTF2B抗体
hz-8169R CBX1/HP1 β 异染色体同源蛋白1抗体
hz-8170R KMT3B/NSD1/ARA267 组蛋白甲基化KMT3B抗体(雄激素受体激活蛋白)
hz-8171R NFIC 核因子1C型抗体
hz-8172R IKAROS 锌指蛋白IKAROS抗体
hz-8173R Dbx2 大脑发育同源蛋白2抗体
hz-8174R HLX1 同源异型盒基因HLX1蛋白抗体
hz-8175R GTF2H1 通用转录因子2H肽1抗体
hz-8176R PHF8 组蛋白赖氨酸去甲基化酶PHF8抗体
hz-8177R KIF11/Eg5/TRIP5 驱动蛋白样蛋白1抗体(甲状腺激素受体相互作用蛋白5)
hz-8178R KDM5C/Jarid1C/SMCX 组蛋白去甲基化Jarid1C抗体
hz-8179R phospho-Eg5(Tyr92) 磷酸化驱动蛋白样蛋白1抗体
hz-8180R COMMD9 铜代谢结构域蛋白9抗体
hz-8181R COMMD10 铜代谢结构域蛋白10抗体
hz-8182R COMMD8 铜代谢结构域蛋白8抗体
hz-8183R COMMD3 铜代谢结构域蛋白3抗体
hz-8184R COMTD1/AVSD2 富含半胱氨酸与表皮生长因子样蛋白2抗体
hz-8185R CRELD2 富含半胱氨酸与表皮生长因子样蛋白2抗体
hz-8186R CRYZL1 醌氧化还原酶样蛋白1抗体
hz-8187R CSMD2 CSMD2蛋白抗体
hz-8188R Histone H3 (mono methyl K79) 单甲基组蛋白H3K9抗体
hz-8189R CCDC18 卷曲螺旋结构域蛋白18抗体
hz-8190R CSMD3 CSMD3蛋白抗体
hz-8191R CSTP1 钙调神经磷酸酶CSTP1抗体
hz-8192R CTAGE6 CTAGE6蛋白抗体
hz-8193R CTAGE4 皮肤T细胞淋巴瘤相关抗原4抗体
hz-8194R FAM40A FAM家族蛋白40A抗体
hz-8195R FAM120B 组织激活过氧化酶活化增生受体γ蛋白抗体
hz-8196R FAM55D FAM55D蛋白抗体
hz-8197R TAAL6 肿瘤相关蛋白抗原L6抗体
hz-8198R FAM46C FAM46C蛋白抗体
hz-8199R FAM168A/TCRP1 舌癌化疗耐药相关蛋白1
hz-4105R Filamin A/FLNA 细丝蛋白A抗体
hz-8200R phospho-MYF5 (phospho Ser49) 磷酸化生肌决定因子Myf5抗体
hz-0438R AT2R/AT1 血管紧张素Ⅱ受体1抗体
hz-8201R PMCA4B 细胞膜钙ATP酶4B抗体
hz-8202R BRN4/POU3F4 脑转录因子4蛋白抗体
hz-5350R phospho-Filamin A/FLNA (Ser2151) 磷酸化细丝蛋白A抗体
hz-5351R phospho-Filamin A/FLNA (Ser2522) 磷酸化细丝蛋白A抗体
hz-1707R Angiotensin I/Angiotensinogen 血管紧张素I抗体
hz-0587R Angiotensin II 血管紧张素Ⅱ抗体
hz-8204R NEEP21 NEEP21蛋白抗体
hz-5354R phospho-Filamin A/FLNA (Tyr1046) 磷酸化细丝蛋白A抗体
hz-3877R Angiotensin III 血管紧张素III抗体
hz-8205R FAM129B FAM129B蛋白抗体