英文名称 RNF167
中文名称 环指蛋白167抗体
别 名 E3 ubiquitin-protein ligase RNF167; RING finger protein 167; RING105; RN167_HUMAN; RNF167.
环指蛋白167抗体
说 明 书 0.1ml 0.2ml
研究领域 细胞生物 免疫学
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
细胞定位 细胞膜
性 状 Lyophilized or Liquid
浓 度 1mg/1ml
免 疫 原 KLH conjugated synthetic peptide derived from human RNF167
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
环指蛋白167抗体产品介绍 background:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Function:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.
Subunit:
Interacts with SLC22A18.
Subcellular Location:
Endomembrane system. Targeted to cytoplasmic membranes.
Tissue Specificity:
Strongly expressed in the kidney and liver (at protein level).
Post-translational modifications:
Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E1.
Similarity:
Contains 1 PA (protease associated) domain.
Contains 1 RING-type zinc finger.
Gene ID:
26001
Database links:
Entrez Gene: 26001 Human
SwissProt: Q9H6Y7 Human
Unigene: 7158 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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