环指蛋白167抗体

英文名称    RNF167    

中文名称    环指蛋白167抗体    

别    名    E3 ubiquitin-protein ligase RNF167; RING finger protein 167; RING105; RN167_HUMAN; RNF167.    

 环指蛋白167抗体      

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    36kDa    

细胞定位    细胞膜     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RNF167    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

 环指蛋白167抗体产品介绍    background:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.

Function:
May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition. 

Subunit:
Interacts with SLC22A18.

Subcellular Location:
Endomembrane system. Targeted to cytoplasmic membranes.

Tissue Specificity:
Strongly expressed in the kidney and liver (at protein level).

Post-translational modifications:
Auto-ubiquitinated in vitro in the presence of UBE2D1 and UBE2E1. 

Similarity:
Contains 1 PA (protease associated) domain. 
Contains 1 RING-type zinc finger. 

Gene ID:
26001

Database links:

Entrez Gene: 26001 Human

SwissProt: Q9H6Y7 Human

Unigene: 7158 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

 环指蛋白167抗体

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