环指蛋白14抗体

英文名称    RNF14    

中文名称    环指蛋白14抗体    

别    名    Androgen receptor associated protein 54; Androgen receptor-associated protein 54; ARA 54; ARA54; E3 ubiquitin protein ligase RNF14; E3 ubiquitin-protein ligase RNF14; FLJ26004; HFB 30; HFB30; HRIHFB2038; RING finger protein 14; RNF 14; Rnf14; RNF14_HUMAN; TRIAD 2; TRIAD2; Triad2 protein.    

环指蛋白14抗体        

说 明 书    0.2ml      

研究领域    细胞生物  信号转导  表观遗传学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    54kDa    

细胞定位    细胞核 细胞浆     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RNF14    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

环指蛋白14抗体产品介绍    background:
Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription.

Function:
Might act as an E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates, which could be nuclear proteins. Could play a role as a coactivator for androgen- and, to a lesser extent, progesterone-dependent transcription. 

Subunit:
Interacts with the ubiquitin-conjugating enzymes UBE2E1 and UBE2E2. Interacts with AR/androgen receptor; testosterone- and RNF6-regulated it promotes AR transcriptional activity.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
RING-type zinc finger-dependent and UBE2E2-dependent autoubiquitination. [SIMILARITY] 

Similarity:
Belongs to the RBR family. RNF14 subfamily. 
Contains 1 IBR-type zinc finger. 
Contains 2 RING-type zinc fingers. 
Contains 1 RWD domain. 

Gene ID:
9604

Database links:

Entrez Gene: 9604 Human

Entrez Gene: 56736 Mouse

Entrez Gene: 619577 Rat

Omim: 605675 Human

SwissProt: Q9UBS8 Human

SwissProt: Q9JI90 Mouse

Unigene: 483616 Human

Unigene: 228903 Mouse

Unigene: 115357 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

环指蛋白14抗体

hz-7113R Fhz 1B  Fhz1B抗体

hz-0037R AIF  调亡诱导因子抗体

hz-4092R BACH1/BRIP1  乳腺癌易感基因相互作用蛋白1抗体

hz-2509R AIMP2  AIMP2抗体

hz-5226R phospho-BACH1/BRIP1(Ser990)  磷酸化乳腺癌易感基因相互作用蛋白1抗体

hz-0299R Adenylate Kinase 1/AK1  腺苷酸激酶-1抗体

hz-4095R CTNNBIP1  β链接素相互作用蛋白1抗体

hz-5265R phospho-CTNNBIP1 (Ser36)  磷酸化β链接素相互作用蛋白1抗体

hz-5266R phospho-CTNNBIP1 (Thr43/Ser50)  磷酸化β链接素相互作用蛋白1抗体

hz-5026R AKR1D1  醛固酮还原酶家族1成员D1抗体

hz-5133R ALDH1B1  乙醛脱氢酶5抗体

hz-4026R ALDOB  醛缩酶2抗体

hz-2406R Aldolase A  醛缩酶A抗体

hz-3976R Aldolase C  醛缩酶C抗体

hz-5139R ALF/GTF2A1LF  通用转录因子IIA样因子抗体

hz-0097R ALK/CD246  间变型淋巴瘤激酶抗体

hz-4096R CDC27/ANAPC3  后期促进复合蛋白3抗体

hz-7501R CO4A2  胶原蛋白4a2亚基抗体

hz-7502R Rhz/GTP binding protein Rhz1  GTP结合蛋白Rhz1抗体

hz-7503R Laminin 1+2  层粘连蛋白1+2抗体

hz-7504R Laminin Beta 2/Laminin S  层粘连蛋白β2抗体

hz-7505R Plakophilin 1  桥粒斑菲素蛋白1抗体

hz-3022R phospho-ALK/CD246(Tyr1604)  磷酸化间变型淋巴瘤激酶抗体

hz-3021R phospho-ALK/CD246(Tyr1278/1282/1283)  磷酸化间变型淋巴瘤激酶抗体

hz-3047R phospho-ALK/CD246(Tyr1586)  磷酸化间变型淋巴瘤激酶抗体

hz-7506R SMOC2  分泌模块化钙结合蛋白2抗体（平滑肌相关蛋白2）

hz-7507R Sprouty 2  快速发育生长因子同源蛋白2抗体

hz-7508R THSD1  血小板跨膜反应蛋白1抗体

hz-7509R VG5Q/AGGF1  血管生长因子VG5Q抗体

hz-7510R stabilin1/STAB 1  淋巴管内皮细胞和血管内皮细胞受体1抗体

hz-7511R UTS2D  尾加压素2相关肽抗体

hz-7512R Hyp/hydroxyproline  羟脯氨酸抗体

hz-7513R BAI1  脑特异性血管生成抑制蛋白1抗体

hz-7514R BAI2/Brain Specific Angiogenesis Inhibitor 2  脑特异性血管生成抑制蛋白2抗体

hz-7515R KLHL20  Kelch样蛋白20抗体

hz-7516R LECT1  白细胞衍生化学吸引素抗体

hz-7517R Natriuretic Peptide Receptor A  利钠肽受体A抗体

hz-7518R Ribonuclease Inhibitor  核糖核酸酶抑制因子1抗体

hz-7519R ShzA4A  跨膜蛋白ShzA4A抗体

hz-7520R SPON1/F spondin  细胞外基质底物反应蛋白1抗体

hz-5267R phospho-CDC27/ANAPC3(Ser427)  磷酸化后期促进复合蛋白3抗体

hz-7521R UCN2/Urotensin II  尾加压素2抗体

hz-7522R TXA2R  血栓素A2受体抗体

hz-5268R phospho-CDC27/ANAPC3(Thr244)  磷酸化后期促进复合蛋白3抗体

hz-7523R phospho-Caveolin-2(Tyr19)  磷酸化细胞质膜微囊蛋白-2抗体

hz-7524R Thrombospondin 2  血小板反应蛋白2/凝血酶敏感蛋白2抗体

hz-7525R TNMD/tenomodulin  腱调蛋白抗体（软骨调节素样1蛋白）

hz-7526R BTG1  B细胞迁移基因1抗体

hz-7527R FAIM3  FAS凋亡抑制分子3抗体

hz-7528R CTRP1/G protein coupled receptor interacting protein 1  G蛋白偶联受体相互作用蛋白1抗体（补体Clq TNF相关蛋白1）

hz-7529R Collagen VIII alpha 1  8型胶原抗体(内皮胶原蛋白)

hz-7530R Creatine Kinase MM  肌酸激酶M型抗体