环指蛋白169抗体

英文名称    RNF169    

中文名称    环指蛋白169抗体    

别    名    KIAA1991; RING finger protein 169; RN169_HUMAN.    

环指蛋白169抗体        

说 明 书    0.1ml  0.2ml      

研究领域    细胞生物  免疫学      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    77kDa    

细胞定位    细胞核     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human RNF169    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

环指蛋白169抗体 产品介绍    background:
RNF169 contains 1 RING type zinc finger. The exact functions of RNF169 remain unknown.

Function:
Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair. 

Subcellular Location:
Nucleus, nucleoplasm. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products. 

Similarity:
Belongs to the RNF169 family. 
Contains 1 RING-type zinc finger.

Gene ID:
254225

Database links:

Entrez Gene: 254225 Human

Entrez Gene: 108937 Mouse

SwissProt: Q8NCN4 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

环指蛋白169抗体 

hz-4801R Salmonella typhimurium  鼠伤寒沙门氏菌

hz-4802R Salmonella paratyphi a  甲型副伤寒沙门氏菌抗体

hz-4803R Salmonella enteritidis/SE  肠炎沙门氏菌抗体

hz-4804R pig cholerae salmonella  猪霍乱沙门氏菌抗体

hz-4805R Duck salmonella  鸭沙门氏菌抗体

hz-4806R USP3  去泛素化酶3抗体

hz-4807R ATXN3L  小脑脊髓共济失调蛋白3抗体

hz-4808R Endomucin  内皮粘蛋白hzCN抗体

hz-4812R KLK3/Prostate Specific Antigen  激肽释放酶3/舒血管素3抗体

hz-4813R H5N1-H5  禽流感H5亚型全病毒抗体

hz-4814R Newcastle disease virus  鸡新城疫疫苗（鸡瘟4型混合病毒）抗体

hz-4815R CD3 epsilon  CD3抗体

hz-4816R CD3 epsilon  CD3抗体

hz-4817R CD4  CD4抗体

hz-4818R CD45/B220  白细胞共同抗原抗体

hz-4819R CD45/B220  白细胞共同抗原抗体

hz-4820R CD45/B220  白细胞共同抗原抗体

hz-4821R AFP  甲胎蛋白AFP抗体

hz-4826R CD83  CD83抗体

hz-4834R CD73/NT5  CD73抗体

hz-4835R MAL/MPV17  T淋巴细胞成熟相关蛋白抗体

hz-4836R CXC-R2  CXCR2/CD182

hz-4838R HE4  附睾分泌蛋白4抗体

hz-4839R nonstructural protein 1/NS1  A型流感病毒-NS1抗体（神经氨酸酶1）

hz-4846R Factor VII  凝血因子7抗体

hz-4847R phospho-ITGB4(Tyr1530)  磷酸化整合素β4抗体

hz-4848R phospho-RUNX3(Ser338)  磷酸化Runx3抗体

hz-4849R GLUT2  葡萄糖转运蛋白2

hz-4850R Collagen II/Chondrocalcin  Ⅱ型胶原α1蛋白/软骨钙素抗体

hz-4851R Collagen II/Chondrocalcin  Ⅱ型胶原α1蛋白/软骨钙素抗体

hz-4852R PIM3  丝氨酸/苏氨酸蛋白激酶PIM3抗体

hz-4856R Hepatitis C Virus NS5a  丙型肝炎病毒NS5A抗体

hz-4857R Hepatitis C Virus NS4B  丙型肝炎病毒NS4B抗体