再生基因蛋白4抗体

英文名称    REG4    

中文名称    再生基因蛋白4抗体    

别    名    Gastrointestinal secretory protein; GISP; REG IV; REG like protein; Regenerating gene type IV; Regenerating islet derived family member 4; Regenerating islet derived protein 4 precursor; REGIV; RELP; REG4_HUMAN.    

再生基因蛋白4抗体       

说 明 书    0.2ml      

研究领域    肿瘤  细胞生物  染色质和核信号  信号转导      

抗体来源    Rabbit    

克隆类型    Polyclonal    

交叉反应    Human, Mouse, Rat, Dog, Pig, Cow,     

产品应用    WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    18kDa    

细胞定位    分泌型蛋白     

性    状    Lyophilized or Liquid    

浓    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human REG4/RELP    

亚    型    IgG    

纯化方法    affinity purified by Protein A    

储 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存条件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

再生基因蛋白4抗体 产品介绍    background:
Reg IV is part of the regenerating gene family within the C-type lectin superfamily. This family is involved in liver, pancreatic, gastric and intestinal cell proliferation and differentiation. Reg IV is a 158-amino acid secretory protein implicated in cell regeneration and/or survival with a definite growth stimulating effect on pancreatic beta cells. It is highly expressed in colorectal, gastric, prostate and other types of cancer. Reg IV-positive tumor cells display different phenotypes including mucus-secreting, enterocyte-like, and undifferentiated.

Function:
May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.

Subcellular Location:
Secreted.

Tissue Specificity:
Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 83998 Human

Omim: 609846 Human

SwissProt: Q9BYZ8 Human

Unigene: 660883 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.    

再生基因蛋白4抗体 

hz-1504P RAP1A (RAS-related protein-1a precursor)  Rap1A抗原

hz-0516P RAR- Beta(Retinoic acid -R- Beta)  维甲酸受体-β抗原

hz-1234P RASSF1A(Ras association domain family 1A)  Ras相关区域家族1A抗原

hz-0795P Resistin  抵抗素抗原

hz-0492P RGS2 peptide  G蛋白信号转导调节因子2抗原

hz-1180P RhoA (RhoA protein)  RhoA抗原

hz-1480P Rho C(Ras homolog gene family mhzber C)  RhoC抗原

hz-2163P RNF148(Ring finger protein 148)  环指蛋白148抗原

hz-1166P ROCK1 (Rho-associated coiled-coil containing protein kinase 1)  Rho相关蛋白激酶1抗原

hz-1205P ROCK2 (Rho-associated coiled-coil containing protein kinase 2)  Rho相关蛋白激酶2抗原

hz-1379P RXR Alpha(retinoid-X receptor alpha)  核受体RXRα抗原

hz-2018P S6PDH(NADP sorbitol-6-phosphate dhzydrogenase)  6-磷酸山梨醇脱氢酶抗原

hz-1248P S100B  S100B蛋白抗原

hz-2015P S100B(S100 calcium binding protein B)(human, mouse, rat, bovine, Rabbit, chicken)  S100B蛋白多肽

hz-0850P S-100A1 (S100 calcium-binding protein A1)  钙结合蛋白S100A1抗原

hz-1609P SATB1(special AT-rich sequence binding protein)  核基质结合区结合蛋白1抗原

hz-0545P SCF (Sthz Cell Factor)  干细胞生长因子抗原

hz-2427P SCN9A/NAV1.7(Sodium channel protein type 9 subunit alpha)  电压开启的钠离子通道SCN9A抗原

hz-1503P CXCL14(CXC-chhzokine ligand 16)  CXC趋化因子14抗原

hz-1441P CXCL16 peptide  CXC趋化因子16抗原

hz-1121P Shza3A (shzaphorin 3A)  臂板蛋白3A(多肽)

hz-1122P Shza3F (shzaphorin 3F)  臂板蛋白3F抗原

hz-1303P SFRP1(Secreted frizzled related protein 1)  分泌型卷曲相关蛋白1抗原

hz-1128P SGLT1(sodium-glucose cotransporter1)  钠-葡萄糖共转运载体1抗原

hz-2149P Shadow/SPRN(Shadow of prion protein precursor)  新朊蛋白/朊蛋白相关蛋白/沙杜（Shadoo）蛋白抗原

hz-0882P Shiga-like toxin IIe variant subunit A 0139[Escherichia coli 0139]  大肠杆菌志贺样毒素Ⅱ型突变体（O139菌型）

hz-0944P Shiga-like toxin IIe variant subunit A[Escherichia coli 0139]  大肠杆菌志贺样毒素菌体蛋白（O139菌型）

hz-1233P SHP2 peptide  蛋白酪氨酸磷酸酶2抗原

hz-1130P SIP1 peptide  运动神经元存活蛋白结合蛋白1抗原

hz-0921P SIRT1(sirtuin 1)  沉默调节蛋白1抗原

hz-1096P Skp2 peptide  细胞S相激酶相关蛋白抗原

hz-2096P SLC4A4(solute carrier family 4:sodium bicarbonate cotransporter NBC1)  碳酸氢钠协同转运蛋白4-A4

hz-1530P Slc4a7/Nbcn1(solute carrier family 4, sodium bicarbonate cotransporter, mhzber 7)  碳酸氢钠协同转运蛋白4-A7抗原